ACTA VETERINARIA ET ZOOTECHNICA SINICA

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Research Progress on Regulation of Imprinted Genes for Animal Placental Phenotype

KANG Qian1,CUI Huan-zhong1*,SUN Yu-cheng2,GAO Yun-hang1,FAN Yi-wen1,LIU Er-zhan1   

  1. (1.College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China; 2.Institute of Military Hippiater, Changchun Academy of Military Medical Sciences, Changchun 130122, China
  • Received:2012-05-31 Online:2013-02-23 Published:2013-02-23

Abstract:

Imprinted genes only express the genetic information from male parent or female parent. A large number of researches showed that imprinted genes have important roles in the fetus growth, fetus development, function of the placenta and postnatal behavior. Imprinted genes have been shown to determine the transport capacity of the placenta by regulating its growth, morphology and transporter capacity. When the environment of placenta or the placenta phenotype changes, the imprinted genes can adapt to the prevailing nutritional environment, by varying their placental epigenetic status. Imprinted genes may act as nutrient sensors and optimize the fetal acquisition of nutrients for growth. These genes have a major role in the epigenetic regulation of placental phenotype.

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