ACTA VETERINARIA ET ZOOTECHNICA SINICA

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Research Progress of Spermatogonial Stem Cells Transplantation Technology

LIU Ling1, ZHU Hua-bin1, WANG Chen1,2, HAO Hai-sheng1, ZHAO Xue-ming1, FENG Rong3, DU Wei-hua1, QIN Tong1, LIU Yan1, WANG Dong1*   

  1. 1. The Key Laboratory for Farm Animal Genetic Resources and Utilization of Ministry of
    Agriculture of China, Institute of Animal Science, Chinese Academy of Agricultural Sciences,
    Beijing 100193,China; 2. Animal Science and Technology College, Guangxi University,
    Nanning 530004,China; 3. Wulanchabu Vocational College, Wulanchabu 012000, China
  • Received:2012-03-02 Online:2012-11-26 Published:2012-11-26

Abstract:

The culture and transplantation of spermatogonial stem cells(SSCs) and related researches will be significant in some fields, such as male infertility, spermatogenesis mechanism research and set-up of transgenic technology. Biological characteristics of mouse SSCs had been studied clearly. The technology system of isolating, purifying and cultivating these stem cells had been built, as well as recipient preparation and transplantation technology. However, the efficiency of these technologies is not high. Reviewing all the above technologies, not only the optimum preparation time of the stem cells can be determined, but also the technique of recipient preparation and the techniques of purification, cultivation and transplantation of SSCs will be improved. And these will also provide guidance for the future study on farm animals in this field.

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