鼠李糖乳杆菌抗炎机制及其在防治家畜疾病中的应用前景

doi:10.11843/j.issn.0366-6964.2023.11.010

Abstract

Abstract: Antibiotics are currently one of the main means of preventing and treating livestock diseases. With the abuse of antibiotics, the resistance of pathogenic bacteria has increased and antibiotic residues in livestock and poultry products have brought great challenges to food safety and disease prevention. As people’s understanding of the abuse of veterinary antibiotics, more and more attention is focused on how to find alternatives to reduce the use of antibiotics. Lactobacillus rhamnosus is mostly found in human and animal intestinal contents, stool, and vagina, also in milk and dairy products. The use of Lactobacillus rhamnosus can reduce the abuse of antibiotics, reduce the problem of drug resistance of pathogenic bacteria, and also promote the growth of livestock and the balance of gastrointestinal microorganisms. The present article reviews the mechanism of Lactobacillus rhamnosus in regulating the balance of microbial flora, maintaining the integrity of epithelial cells, enhancing immunity, inhibiting inflammation and apoptosis, and inhibiting the growth and adhesion of pathogens. At the same time, the application of Lactobacillus rhamnosus in the prevention of dairy cow mastitis, dairy cow endometritis, piglet gastroenteritis and poisoning was described, aiming to provide reference for the application of Lactobacillus rhamnosus as a potential alternative drug in healthy breeding of livestock.

Key words: Lactobacillus rhamnosus, dairy cow endometritis, dairy cow mastitis, piglet gastroenteritis, poison

CLC Number:

S859.79.7

SHAN Qiang, WANG Xue, ZHU Yaohong, WANG Jiufeng. Application Prospect of Anti-inflammatory Mechanism of Lactobacillus rhamnosus and Its Prevention and Treatment in Livestock Diseases[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(11): 4537-4550.

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Application Prospect of Anti-inflammatory Mechanism of Lactobacillus rhamnosus and Its Prevention and Treatment in Livestock Diseases

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