ACTA VETERINARIA ET ZOOTECHNICA SINICA

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Effect of Chromium Picolinate on Ca2+ Concentration of Lymphocyte and Immune Response from Heat Stress Broiler Chickens

HAN Ai-yun1,2, ZHANG Min-hong1*, FENG Jing-hai1   

  1. (1. State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China; 2. School of Chemical Engineering,Shijiazhuang University,Shijiazhuang 050035, China
  • Received:2012-05-15 Online:2013-02-23 Published:2013-02-23

Abstract:

The experiment was conducted to investigate the effect of chromium picolinate (CrPic) on Ca2+ concentration of lymphocyte and immune response from heat stress broiler chickens. Three hundred 1-day-old Arbor Acres male broiler chickens were randomly allotted to 5 treatments (Ⅰ-Ⅴ), each treatment represented by 5 replicates of 12 birds each. At 15-day-old,the broilers in treatmentⅠ-Ⅳ were pre-fed 0, 400,800,1 200 μg·kg-1 Cr of diet for 2 weeks, then they were housed in 3 controlled environment chambers with daily high cyclic temperature (27 ℃—35 ℃—27 ℃) for 14 d, the broilers in treatment Ⅴ were kept in 22 ℃ as the control group. The result shows that supplemental chromium (800-1 200 μg·kg-1 Cr) decreased serum insulin concentration, supressed the increasement of the lymphocytes [Ca2+i and IL-2 concentration, increased the lymphocyte proliferation. The results sugget that the CrPic could alleviate the negative effect of heat stress on the cellular immune response of heat stress broiler chickens.

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