产后不同挤奶时间对初乳品质及不同品质初乳对新生犊牛被动免疫转移的影响

doi:10.11843/j.issn.0366-6964.2025.08.026

Abstract

Abstract:

The aim of this study was to investigate the effects of different milking time on colostrum quality and the effects of colostrum quality on passive immunity and serum biochemical parameters of newborn calves. According to the time interval between delivery and milking, 329 cows on verge of delivery and at the second parity with good body condition were divided into four groups: Milking within 2 h after delivery, milking 2~4 h after delivery, milking 4~8 h after delivery and milking more than 8~12 h after delivery. The effect of different milking time after delivery on the content of immunoglobulin G (IgG) in colostrum was determined. Forty-five Holstein female calves (38 ±2 kg) with similar birth date were selected and randomly divided into three groups: High quality colostrum group, medium colostrum group and low quality colostrum group, with 15 calves in each group. Calves were fed with three different quality colostrum using the 4+2 feeding mode (4 L colostrum was given within 2 h after birth and 2 L colostrum was given 6 h after birth). The levels of IgG in colostrum were 63.8, 37.6 and 15.6 mg ·mL^-1, respectively. Blood samples were collected from all calves after birth(0 h), 24 h and 48 h after colostrum feeding (within 2 h after birth), and the contents of total protein (TP), IgG, albumin (ALB), C3 and C4 in serum were analysed. The results showed that: 1) The IgG content of colostrum milked within 2 h after delivery was significantly higher than that of colostrum milked at 2~4 h, 4~8 h and more than 8 h after delivery (P < 0.01). 2) There was no significant difference in serum TP and IgG content among the three groups before colostrum was fed. At 24 h and 48 h after colostrum was fed, the serum TP and IgG content of the high quality colostrum group were significantly higher than those of the medium colostrum group and the low quality colostrum group (P < 0.01). 3) The average serum IgG content at 24 h and 48 h in high quality colostrum group and medium colostrum group were more than 10 mg ·mL^-1 (the minimum IgG content for successful passive immunity of calves). In low quality colostrum group, the serum IgG content of 5 calves was less than 10 mg ·mL^-1 at 24 h, accounting for 33.3% of calves in this group, and the serum IgG content of 4 calves was less than 10 mg ·mL^-1 at 48 h, accounting for 26.7% of calves in this group. In conclusion, the shorter milking interval after delivery, the higher the quality of colostrum, and the highest content of IgG in colostrum was found when the milking interval was controlled within 2 h. High quality colostrum contributes to the successful passive immunity of newborn calves and has beneficial effects on serum biochemical parameters.

Key words: calves, colostrum quality, passive immunity transfer, serum immune indicators

CLC Number:

TS252.1

BAO Xiaoping, CUI Junwei, ZHAO Yulong, GUO Cheng, CHEN Ming, BI Yanliang. Effects of Different Milking Time after Delivery on Colostrum Quality and the Impact of Different Quality Colostrum on Passive Immune Transfer in Newborn Claves[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56(8): 3861-3871.

Figures/Tables 6

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References 41

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项目 Item	产后挤奶时间 Post-calving milking intervals				SEM	P值 P-value
项目 Item	2 h	2~4h	4~8 h	8~12 h	SEM	P值 P-value
初乳IgG Colostrum IgG	97.85^A	78.72^B	62.34^C	48.60^D	1.477	＜0.01

处理组 Treatment	犊牛头数 Number of calves	初乳中IgG的含量/(mg·mL^－1) The content of IgG in colostrum	饲喂初乳量/L Colostrum feeding volume		6 h IgG的摄入量/g 6 h IgG intake
处理组 Treatment	犊牛头数 Number of calves	初乳中IgG的含量/(mg·mL^－1) The content of IgG in colostrum	0 h	6 h	6 h IgG的摄入量/g 6 h IgG intake
高IgG组 High IgG group	15	63.80	4.00	2.00	382.80
中IgG组 Medium IgG group	15	37.60	4.00	2.00	225.60
低IgG组 Low IgG group	15	15.60	4.00	2.00	93.60

项目 Item	时期 Period	处理组Treatment			SEM	P值P-value
项目 Item	时期 Period	高IgG组 High IgG group	中IgG组 Medium IgG group	低IgG组 Low IgG group	SEM	T	W	W×T
TP/(g·dL^－1)	整个试验期	5.92^Aa	5.47^Bb	5.24^Bc	0.016	＜0.01	＜0.01	＜0.01
	0 h	4.60	4.57	4.62	0.017	0.95
	24 h	6.65^Aa	5.96^Bb	5.51^Bc	0.015	＜0.01
	48 h	6.52^Aa	5.87^Bb	5.58^Bc	0.021	＜0.01
IgG/(mg·mL^－1)	整个试验期	16.48^A	11.45^B	9.32^C	0.009	＜0.01	＜0.01	＜0.01
	0 h	0.05	0.06	0.05	0.002	0.93
	24 h	25.64^A	17.54^B	13.68^C	0.017	＜0.01
	48 h	23.76^Aa	16.74^Bb	14.24^Bc	0.011	＜0.01

项目 Item	处理组Treatment			SEM	P值 P-value
项目 Item	高IgG组 High IgG group	中IgG组 Medium IgG group	低IgG组 Low IgG group	SEM	P值 P-value
吸收率/% Absorption rate	20.57^b	21.08^b	32.57^a	1.270	0.04

项目 Item	时间 Period	处理组Treatment			SEM	P值P-value
项目 Item	时间 Period	高IgG组 High IgG group	中IgG组 Medium IgG group	低IgG组 Low IgG group	SEM	T	W	T×W
ALB/(g·dL^－1)	整个试验期	3.26^A	3.14^B	3.10^C	0.009	＜0.01	0.04	＜0.01
	0 h	3.03	3.02	3.04	0.007	0.93
	24 h	3.24^A	3.15^B	3.09^C	0.014	＜0.01
	48 h	3.51^A	3.24^B	3.17^C	0.012	＜0.01
C3/(g·L^－1)	整个试验期	0.12^A	0.12^A	0.09^B	0.001	＜0.01	0.84	0.23
	0 h	0.09	0.09	0.09	0.001	0.87
	24 h	0.13^A	0.12^A	0.09^B	0.002	＜0.01
	48 h	0.15^A	0.14^A	0.11^B	0.001	＜0.01
C4/(g·L^－1)	整个试验期	0.09^A	0.09^A	0.08^B	0.001	＜0.01	0.75	0.31
	0 h	0.07	0.06	0.07	0.001	0.93
	24 h	0.09^A	0.09^A	0.08^B	0.002	＜0.01
	48 h	0.11^A	0.11^A	0.08^B	0.001	＜0.01

Effects of Different Milking Time after Delivery on Colostrum Quality and the Impact of Different Quality Colostrum on Passive Immune Transfer in Newborn Claves

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