Acta Veterinaria et Zootechnica Sinica ›› 2023, Vol. 54 ›› Issue (5): 2013-2019.doi: 10.11843/j.issn.0366-6964.2023.05.022

• ANIMAL NUTRITION AND FEEDS • Previous Articles     Next Articles

Effects of Dietary Lysine Supplementation on Hair Production Performance and Hair Follicle Development of Angora Rabbits

LI Yujuan, ZHANG Yuanming, ZHANG Beiyu, LI Fuchang, LIU Lei*   

  1. School of Animal Science and Technology, Shandong Agricultural University, Tai'an 271018, China
  • Received:2022-08-22 Online:2023-05-23 Published:2023-05-20

Abstract: The objective of this experiment was to explore the effects of dietary different levels of lysine on the hair production performance and hair follicle development of Angora rabbits. One hundred and sixty Angora rabbits with good growth and development status (10 months old) were selected and randomly divided into 4 groups. The control group was fed basic diet, and the experimental groups were fed basic diet with an addition of 0.25%, 0.35% or 0.45% lysine, respectively. The experimental period lasted for 65 days. The results showed that:The addition of 0.25% lysine to diet significantly increased hair yield, hair yield ratio, feed conversion rate, total follicle density and secondary follicle density (P<0.05). The addition of 0.25% lysine in diet significantly increased the gene expression of the Wnt family 10b protein (Wnt10b), β-catenin (β-catenin), and rapamycin target protein (mTOR) in the skin (P<0.05). The addition of 0.35% lysine in diet significantly increased the expression of keratin-associated protein (Kap6.1) gene and also significantly reduced the expression of transforming growth factor (TGF-β1) gene (P<0.05). Dietary addition of lysine can promote the development of skin follicles in rabbits, and Wnt10b/β-catenin, TGF-β and Kap signaling pathways may be involved in the regulatory process.

Key words: lysine, Angora rabbit, hair follicle development, hair production performance

CLC Number: