Acta Veterinaria et Zootechnica Sinica ›› 2023, Vol. 54 ›› Issue (2): 421-433.doi: 10.11843/j.issn.0366-6964.2023.02.001

• REVIEW • Previous Articles     Next Articles

Single-Cell Transcriptome Sequencing Technology and its Application in Animal Reproduction

LIU Yuanyi1, LI Xinyu1, Bayinnamula1, CUI Fang2, MANG Lai1, DU Ming1*   

  1. 1. Key Laboratory of Genetics, Breeding and Reproduction of Horse Genusin ofInner Mongolia Autonomous Region, College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China;
    2. Animal Disease Prevention and Control Center of Alukeerqin Banner, Chifeng 025550, China
  • Received:2022-08-15 Online:2023-02-23 Published:2023-02-21

Abstract: Animal reproduction plays a crucial role in community continuation, species evolution, and evolutionary variation in animal population development and life evolution. Reproduction results from the dynamic changes and interaction effects of various germ cells. The analysis of the dynamic change mechanism of germ cells is the basis for understanding the reproductive process of animals. Single-cell transcriptome sequencing technology deeply interprets information in a single-cell dimension in population cells. It gradually becomes the primary choice for interpreting complexes, diverse and dynamic biological problems such as cell group heterogeneity, key gene screening, related pathway expression, and cell interaction. Currently, single-cell transcriptome sequencing technology has begun to explore the related mechanisms of animal reproduction from the perspective of animal germ cells to study the related processes of animal reproduction further. Therefore, this paper summarizes the related content of single-cell transcriptome sequencing technology and its application in animal reproduction.

Key words: single-cell transcriptome sequencing, animal reproduction, germ cells

CLC Number: