Abstract: Complex and diverse intestinal microbial communities play an important role in the host health. Butyrate-producing bacteria represent an important functional group in host intestinal microecology, and most of them are Gram-positive anaerobic bacteria. It is found that butyrate-producing bacteria are closely related to the gastrointestinal inflammation caused by microbial imbalance, so butyrate-producing bacteria became an industry research hotspot. Many studies have shown that butyrate-producing bacteria can confer a health benefit on the host by producing butyrate with indigestible carbohydrates to maintain intestinal bacterial balance, supply energy for intestinal epithelial cells and enhances the function of intestinal mucosal barrier. The biological classification distribution of butyrate-producing bacteria, the mechanism of digestive tract acid production, the regulation of intestinal inflammation and its application progress are systematically reviewed in this paper, in order to elucidate the mechanism of the interaction between butyrate-producing bacteria and host health, and future directions for butyrate producing bacteria are suggested as well.

Key words: butyrate-producing bacteria, acid producing mechanism, intestinal microorganism, intestinal inflammation, host health