电针百会穴对脾虚泄泻模型大鼠影响的研究

doi:10.11843/j.issn.0366-6964.2022.03.027

Abstract

Abstract: This study aims at exploring the effect of electric acupuncture at Baihui acupoint on rats with spleen-deficiency diarrhea. Sixty-four Wistar rats were selected and divided into four groups:sham operation group (Sham), model group (Model), electric acupuncture Baihui group (Baihui), positive control group (PC). Except for the Sham group, the rest groups were established spleen-deficiency diarrhea model by gavage of Folium Sennae decoction. The rats of Baihui group were electro-acupunctured at the Baihui acupoint and the rats of PC group were gavaged with montmorillonite powder for 2 weeks after successful modeling. During the whole experiment, the symptoms and signs, body mass and diarrhea index of all rats were observed and recorded. After the experiment, the serum levels of D-xylose, amylase (AMS), and inflammatory factors such as interleukin-2 (IL-2), IL-12, and tumor necrosis factor-α (TNF-α) of all rats were detected. The spleen and pancreas were taken out, and the indexes of spleen and pancreas were measured. The results showed that the rats in the Model group suffered from weight loss, sluggish spirit, messy hair, decreased activity, watery stools, and perianal and tail adhering to loose stools. Electric acupuncture at Baihui acupoint could gradually restore the general behavioral state of rats with spleen-deficiency diarrhea, and significantly increase the body mass of male rats (P<0.05), decrease the diarrhea index (P<0.05), increase the content of serum D-xylose and amylase (P<0.05), decrease the serum content of IL-2, IL-12, and TNF-α (P<0.05). The results demonstrated that electric acupuncture the Baihui acupoint could improve the symptoms and signs of rats with spleen-deficiency diarrhea, increase body mass, adjust organ index, improve digestion and absorption, and relieve inflammation. Therefore, it has a certain therapeutic effect. This study provides a quick and convenient treatment method for clinical treatment of spleen-deficiency diarrhea, and could also provide a theoretical basis for the study of the efficacy and mechanism of Baihui acupoint.

Key words: electric acupuncture, Baihui acupoint, spleen-deficiency diarrhea

CLC Number:

S853.6

ZHOU Ke, NIU Chun, LIU Wenjuan, YAO Wanling, JI Peng, HUA Yongli, WEI Yanming. Study on the Effect of Electric Acupuncture at Baihui Acupoint on Rats with Spleen-deficiency Diarrhea[J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(3): 947-955.

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Study on the Effect of Electric Acupuncture at Baihui Acupoint on Rats with Spleen-deficiency Diarrhea

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