食源性病原菌激发固有免疫细胞胞外诱捕网的研究进展

doi:10.11843/j.issn.0366-6964.2021.07.004

Abstract

Abstract: Innate immune cells release fibrous net substances which are composed of chromatin DNA and various intracellular protein components to the extracellular environment after being stimulated by exogenous substances. Those substances are called extracellular traps (ETs). ETs are new types of host defense mechanism that can capture or kill pathogens, control the spread of pathogens, and protect the body from infection. Diseases caused by foodborne zoonotic pathogens, such as Escherichia coli and Salmonella, are public health issues of widespread concern worldwide. This article reviews the research progress of the formation of ETs stimulated by foodborne pathogens, the biological activity of ETs, and the influence of some bacterial proteins on the formation of ETs. This article is intended to provide theoretical reference for the prevention and control of foodborne diseases.

Key words: foodborne pathogens, extracellular traps, innate immune cells, defense mechanism

CLC Number:

S852.42

QIAN Man, LIAO Chengshui, ZHANG Chunjie. Research Progress on Extracellular Traps of Innate Immune Cells Stimulated by Foodborne Pathogens[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(7): 1800-1808.

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Research Progress on Extracellular Traps of Innate Immune Cells Stimulated by Foodborne Pathogens

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