抗球虫药物残留的免疫检测技术

doi:10.11843/j.issn.0366-6964.2021.04.006

Abstract

Abstract: Anticoccidial drugs are widely used in livestock and poultry industry to prevent and treat coccidiosis. It can improve feed conversion rate and meat quality. However, the problems, such as feed cross-contamination, toxic effects on non-target animals and excessive drug residues in animal food, are subsequently appeared. Therefore, it is crucial to establish simple, rapid, and sensitive methods for the detection of anticoccidial drug residues in the food of animal origin. The immunoassay technology based on the principle of antigen-antibody specific binding can complete rapid detection and high-throughput screening. It has the advantages of strong specificity, high sensitivity, simple operation, and low cost. This paper reviewed the development of immunoassay techniques for the detection of anticoccidial drug residues in different matrix. Enzyme linked immunosorbent assay, immunochromatography, fluorescence polarization immunoassay, time-resolved fluoroimmunoassay and biosensor immunoassay were highlighted. The trendency of immunoassay in residue detection was also prospected. It aimed to provide methodological reference for the monitoring of anticoccidial drug residues and provide ideas for the establishment of new methods.

Key words: anticoccidial drugs, residue detection, immunoassay, food of animal origin

CLC Number:

S859.84

CHEN Yingxian, MA Yuejiao, LI Jiancheng. A Review of Immunoassay for the Determination of Coccidiostats Residues[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(4): 899-908.

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A Review of Immunoassay for the Determination of Coccidiostats Residues

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