皖西白鹅换羽前后基因表达谱差异分析

doi:10.11843/j.issn.0366-6964.2013.07.006

Abstract

Abstract:

The aim of this study was to exploit genes that play key roles during feather regeneration. In this experiment, 6 female Wanxi-white geese with 100-day-old were selected for skin samples before and 1 d after moulting. The 6 RNA samples were equally mixed for detecting the differentially expressed genes before and after moulting in Wanxi-white goose. The results showed that Wnt5a, Wnt10a and Lipoprotein receptor-related protein 3 (LRP3) genes in Wnt signaling pathway were down-regulated, and wnt receptors genes (frizzled 2 (FZD2), FZD9 and SFRP2) were up-regulated while FRZB, FZD8 and FZD10 were down-regulated 1 d after moulting in Wanxi-white goose. In the Noggin signaling pathway, NOG2 and NOG were down-regulated, and BMPR1A and BMP1 were up-regulated while BMP2, BAMPI, BMP2 and BMP7 were down-regulated 1 d after moulting. Cell cycle-related protein Cyclin B3 and Cyclin Y were up-regulated while Cyclin D3 and CDK3 were down-regulated. Other genes, such as IGF2, IGFα, IL6ST, TNFSF15, were also detected as differentially expressed genes 1 d after moulting in Wanxi-white goose. Many genes which participated in Wnt signaling pathway and Noggin signaling pathway, were detected in differential expression 1 d after moulting in Wanxi-white goose. The differentially expressed genes detected in this experiment would provide more information in the molecular regulation of downy feather regeneration. Genes screened from this experiment might be taken as key regulatory genes for breeding of goose with high-yield downy feather.

CLC Number:

S835
S813.3

CHEN Xing-yong, XIE Shan-shan, ZHOU Li, JIANG Run-shen, GENG Zhao-yu. Identification of Differentially Expressed Genes in Skin of Wanxi-white Goose during Regeneration of Downy Feather[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2013, 44(7): 1030-1036.

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Identification of Differentially Expressed Genes in Skin of Wanxi-white Goose during Regeneration of Downy Feather

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