动物源产气荚膜梭菌耐药性研究进展

doi:10.11843/j.issn.0366-6964.2021.010.007

摘要/Abstract

摘要： 细菌耐药性是21世纪人类面临的重大公共卫生安全问题之一。产气荚膜梭菌作为一种重要的人兽共患病原菌，能引起人和动物食物中毒、气性坏疽、坏死性肠炎等多种疾病。随着临床抗菌药物的广泛使用，其耐药性也在不断发展，严重威胁着公共卫生安全和养殖业的健康发展。本文将从产气荚膜梭菌近十年来的耐药性流行情况、耐药机制及耐药基因传播机制两个方面进行归纳总结，旨在为产气荚膜梭菌耐药性的防控提供理论依据。

关键词: 产气荚膜梭菌, 抗生素耐药性, 公共卫生健康

Abstract: Antibiotic resistance is one of the most severe threats to public health in the 21st century. As an important zoonotic and food-borne pathogen, Clostridium perfringens (C. perfringens) could cause food poisoning, gas gangrene, necrotizing enteritis in humans and animals. The extensive use of antibiotics promotes the resistance of C. perfringens continuously, seriously threaten the public health and the economic benefits of animal husbandry. This review focuses on the occurrence of antimicrobial resistance in the last decade, and the antibacterial mechanism in C. perfringens of common antibiotics, in a bid to provide scientific insight for the prevention and control of antibiotic resistance.

Key words: Clostridium perfringens, antibiotic resistance, public health

中图分类号:

S852.61

张仕泓, 王少林. 动物源产气荚膜梭菌耐药性研究进展[J]. 畜牧兽医学报, 2021, 52(10): 2762-2771.

ZHANG Shihong, WANG Shaolin. Research Progress on Antimicrobial Resistance of Clostridium perfringens of Animal Origins[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(10): 2762-2771.

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