[1]BLACHIER F, MARIOTTI F, HUNEAU J F, et al. Effects of amino acid-derived luminal metabolites on the colonic epithelium and physiopathological consequences [J]. Amino Acids, 2007, 33(4): 547-562.
[2]WINDMUELLER H G. Glutamine utilization by the small intestine [J]. Adv Enzymol Relat Areas Mol Biol, 1982, 53:201-237.
[3]FOUILLET H, JUILLET B, BOS C, et al. Urea-nitrogen production and salvage are modulated by protein intake in fed humans: results of an oral stable-isotope-tracer protocol and compartmental modeling [J]. Am J Clin Nutr, 2008, 87(6): 1702-1714.
[4]STOLL B, HENRY J, REEDS P J, et al. Catabolism dominates the first-pass intestinal metabolism of dietary essential amino acids in milk protein-fed piglets [J]. J Nutr, 1998, 128(3): 606-614.
[5]HÄUSSINGER D. Ammonia, urea production and pH regulation[M]. 3rd Edition. The textbook of hepatology: from basic science to clinical practice. Eds Rodes J, Benhamou JP, Blei A, Reichen J and Rizzetto M. Wiley-Blackwell, 2007: 181-192.
[6]黄飞若. 猪营养代谢与表观遗传学[M]. 北京:化学工业出版社, 2016.
HUANG F R. Porcine nutrition metabolism and epigenetic [M]. Beijing: Chemical Industry Press, 2016.(in Chinese)
[7]MILANO G D, HOTSTON-MOORE A, LOBLEY G E. Influence of hepatic ammonia removal on ureagenesis, amino acid utilization and energy metabolism in the ovine liver [J]. Br J Nutr, 2000, 83(3): 307-315.
[8]YANG D, HAZEY J W, DAVID F, et al. Integrative physiology of splanchnic glutamine and ammonium metabolism [J]. Am J Physiol Endocrinol Metab, 2000, 278(3): E469-E476.
[9]BROSNAN J T, BROSNAN M E, YUDKOFF M, et al. Alanine metabolism in the perfused rat liver. Studies with (15)N [J]. J Biol Chem, 2001, 276(34): 31876-31882.
[10]LI L, ZHANG P, BAO Z, et al. PGC-1α promotes ureagenesis in mouse periportal hepatocytes through SIRT3 and SIRT5 in response to glucagon[J]. Sci Rep, 2016, 6: 24156.
[11]YIN Y L, HUANG R L, LI T J, et al. Amino acid metabolism in the portal-drained viscera of young pigs: effects of dietary supplementation with chitosan and pea hull[J]. Amino Acids, 2010, 39(5): 1581-1587.
[12]郑培培,包正喜,李鲁鲁,等.肝脏营养物质代谢的仔猪肝-门静脉血插管技术的建立[J].动物营养学报,2014,26(6):1624-1631.
ZHENG P P, BAO Z X, LI L L, et al. Establishment of techniques for implanting hepatic-portal catheters in piglets for studying hepato-nutrients metabolism [J]. Chinese Journal of Animal Nutrition, 2014, 26(6): 1624-1631. (in Chinese)
[13]BUSH J A, WU G, SURYAWAN A, et al. Somatotropin-induced amino acid conservation in pigs involves differential regulation of liver and gut urea cycle enzyme activity[J]. J Nutr, 2002, 132(1): 59-67.
[14]贾逸敏. 母猪低蛋白日粮对新生仔猪肝脏糖异生和肝脏线粒体功能的影响及其表遗传机制[D]. 南京: 南京农业大学, 2012.
JIA Y M. Effect of maternal low protein dietary on hepatic gluconeogenesis and mitochondrial function in newborn piglets and its epigenetic mechanisms [D]. Nanjing: Nanjing Agricultural University, 2012. (in Chinese)
[15]LIVAK K J, SCHMITTGEN T D. Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method [J]. Methods, 2001, 25(4): 402-408.
[16]VOLLMAR B, MENGER M D. The hepatic microcirculation: mechanistic contributions and therapeutic targets in liver injury and repair [J]. Physiol Rev, 2009, 89(4): 1269-1339.
[17]BROSNAN J T, BROSNAN M E. Hepatic glutaminase-a special role in urea synthesis?[J]. Nutrition, 2002, 18(6): 455-457.
[18]HÄUSSINGER D. Regulation of hepatic ammonia metabolism: the intercellular glutamine cycle [J]. Adv Enzyme Regul, 1986, 25: 159-180.
[19]HÄUSSINGER D. Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver [J]. Eur J Biochem, 1983, 133(2): 269-275.
[20]MORRIS S M Jr. Regulation of enzymes of urea and arginine synthesis [J]. Annu Rev Nutr, 1992, 12: 81-101.
[21]LOBLEY G E, CONNELL A, LOMAX M A, et al. Hepatic detoxification of ammonia in the ovine liver: possible consequences for amino acid catabolism [J]. Br J Nutr, 1995, 73(5): 667-685.
[22]NISSIM I, YUDKOFF M, BROSNAN J T. Regulation of [15N] urea synthesis from [5-15N] glutamine. Role of pH, hormones, and pyruvate [J]. J Biol Chem, 1996, 271(49): 31234-31242. |