矛形双腔吸虫病检测方法与防治技术

doi:10.11843/j.issn.0366-6964.2025.07.009

摘要/Abstract

摘要：

双腔吸虫病是由矛形双腔吸虫寄生于牛、羊等反刍动物肝胆管、胆囊内引起的一种寄生虫病。患病动物临床表现为消瘦、四肢迟缓、食欲废绝、腹泻等渐进性衰弱症状，最终因感染加重、衰竭而亡。目前矛形双腔吸虫病尚无长效安全疫苗可用，加之全球性耐药性问题愈烈，严重威胁公共卫生安全，造成巨大的经济损失。对于该病的防控，关键是早期检测及准确诊断、制定合理驱虫方案、定期耐药监测及流行病学调查。本文总结了近三十年来矛形双腔吸虫病的检测技术现状和防治手段，比对分析病原学、血清学、分子生物学等检测方法的优缺点，阐述常见抗矛形双腔吸虫药物的临床不良反应，以期为该病新型微量检测技术的后续研发和综合防控策略的完善提供科学参考。

关键词: 矛形双腔吸虫, 病原学检测, 血清学检测, 诊断, 防治

Abstract:

Dicrocoeliasis is a parasitic disease caused by Dicrocoelium dendriticum, which primarily infects the hepatic bile duct and gallbladder of ruminants such as cattle and sheep. Infected animals exhibit clinical signs including weight loss, lethargy, anorexia, diarrhea, and other progressive debilitating symptoms that can ultimately lead to mortality due to the aggravation of infection. At present, there is no long-term safe vaccine available, and the escalating issue of global drug resistance poses significant threats to public health while incurring substantial economic losses. Effective prevention and control strategies rely on early detection, precise diagnosis, judicious deworming protocols, regular monitoring for drug resistance, and comprehensive epidemiological investigations. This paper reviews advancements in detection technologies and preventive measures for dicrocoeliasis over the past three decades; it critically compares the strengths and limitations of etiological, serological, and molecular biological detection methods while elucidating the clinical adverse reactions associated with commonly used anti-dicrocoeliasis medications. The objective is to provide a scientific foundation for future research into novel micro-detection technologies as well as enhancements in comprehensive prevention strategies.

Key words: Dicrocoelium dendriticum, etiological detection, serological test, diagnosis, prevention and cure

中图分类号:

S855.9

戴钰茵, 李江, 代国年, 朱莉, 李冰, 周绪正, 张继瑜. 矛形双腔吸虫病检测方法与防治技术[J]. 畜牧兽医学报, 2025, 56(7): 3129-3141.

DAI Yuyin, LI Jiang, DAI Guonian, ZHU Li, LI Bing, ZHOU Xuzheng, ZHANG Jiyu. Advances in Detection Approaches and Control of Dicrocoeliasis[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56(7): 3129-3141.

图/表 1

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