母牛早期妊娠诊断技术研究进展

doi:10.11843/j.issn.0366-6964.2023.06.002

摘要/Abstract

摘要： 简单、准确的早期妊娠诊断,是减少空怀,提升母畜繁殖力、提高养殖场经济效益的重要手段。直肠触诊、B超检查、孕酮检测等传统妊娠诊断方法,虽然为养殖生产提供了重要技术支撑,但还未实现母牛配后最早检测,部分养殖场还难以满足较高的技术要求或实验室条件。胚胎滋养层细胞分泌的妊娠相关蛋白(PAGs)是奶牛妊娠过程中的重要蛋白,其血液含量变化规律为妊娠诊断方法研发提供了新思路。本文简要概述了现有妊娠诊断方法,详细论述PAGs诊断方法发展历程,展望未来妊娠诊断技术发展方向,使其在"早"、"准"、"简便性"上取得重要进展,并为相关研究提供了重要参考。

关键词: 早期妊娠诊断, 牛妊娠相关蛋白, 自动化, 中红外光谱

Abstract: Simple and accurate early pregnancy diagnosis is an important means to reduce open cows, improve female fecundity and improve farm economic benefits. Although traditional pregnancy diagnoses methods such as rectal palpation, B-ultrasound examination, and progesterone detection have provided important technical support for breeding production, they have not yet achieved the earliest detection of cows after mating, and some farms are still difficult to meet the high technical requirements or laboratory conditions. Pregnancy-associated proteins (PAGs) are pregnancy-specific proteins secreted by embryonic trophoblast cells, which play an important role in the pregnancy of dairy cows and are widely used in the diagnosis of early pregnancy in dairy cows. This article briefly summarizes the existing diagnostic methods for pregnancy, discusses the development process of PAGs diagnostic methods in detail, looks forward to the future development direction of pregnancy diagnostic technology, and makes important progress in "early", "accurate" and "simple", and provides relevant research information and important reference.

Key words: early pregnancy diagnosis, bovine pregnancy-associated protein, automation, mid-infrared spectroscopy

中图分类号:

S823.3

原开敏, 时玉新, 董智豪, 赵羚均, 许师源, 吴开慧, 王栋. 母牛早期妊娠诊断技术研究进展[J]. 畜牧兽医学报, 2023, 54(6): 2223-2230.

YUAN Kaimin, SHI Yuxin, DONG Zhihao, ZHAO Lingjun, XU Shiyuan, WU Kaihui, WANG Dong. Research Progress on Early Pregnancy Diagnosis Technologies in Cows[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(6): 2223-2230.

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