饲粮赖氨酸水平对安哥拉兔产毛性能及毛囊发育的影响

doi:10.11843/j.issn.0366-6964.2023.05.022

摘要/Abstract

摘要： 旨在探究饲粮添加不同水平赖氨酸对安哥拉兔产毛性能以及毛囊发育的影响。试验选取10月龄生长发育状况良好的安哥拉兔公兔160只,随机分为4组。对照组饲喂基础饲粮,试验组在基础饲粮的基础上再添加0.25%、0.35%、0.45%的赖氨酸,试验期65 d。结果表明:饲粮添加0.25%的赖氨酸显著提高了产毛量、产毛率、饲料转化效率、总毛囊密度和次级毛囊密度(P<0.05)。饲粮添加0.25%的赖氨酸显著增加皮肤中Wnt家族10b蛋白(Wnt10b)、β-连环蛋白(β-catenin)、雷帕霉素靶蛋白(mTOR)的基因表达量(P<0.05)。饲粮添加0.35%的赖氨酸显著提高了角蛋白相关蛋白(Kap6.1)基因表达量,也显著降低转化生长因子(TGF-β1)基因表达量(P<0.05)。由此可见,饲粮中添加赖氨酸可促进长毛兔皮肤毛囊发育,Wnt10b/β-catenin、TGF-β和Kap信号通路可能参与此调节过程。

关键词: 赖氨酸, 安哥拉兔, 毛囊发育, 产毛性能

Abstract: The objective of this experiment was to explore the effects of dietary different levels of lysine on the hair production performance and hair follicle development of Angora rabbits. One hundred and sixty Angora rabbits with good growth and development status (10 months old) were selected and randomly divided into 4 groups. The control group was fed basic diet, and the experimental groups were fed basic diet with an addition of 0.25%, 0.35% or 0.45% lysine, respectively. The experimental period lasted for 65 days. The results showed that:The addition of 0.25% lysine to diet significantly increased hair yield, hair yield ratio, feed conversion rate, total follicle density and secondary follicle density (P<0.05). The addition of 0.25% lysine in diet significantly increased the gene expression of the Wnt family 10b protein (Wnt10b), β-catenin (β-catenin), and rapamycin target protein (mTOR) in the skin (P<0.05). The addition of 0.35% lysine in diet significantly increased the expression of keratin-associated protein (Kap6.1) gene and also significantly reduced the expression of transforming growth factor (TGF-β1) gene (P<0.05). Dietary addition of lysine can promote the development of skin follicles in rabbits, and Wnt10b/β-catenin, TGF-β and Kap signaling pathways may be involved in the regulatory process.

Key words: lysine, Angora rabbit, hair follicle development, hair production performance

中图分类号:

S829.141

李玉娟, 张原铭, 张北育, 李福昌, 刘磊. 饲粮赖氨酸水平对安哥拉兔产毛性能及毛囊发育的影响[J]. 畜牧兽医学报, 2023, 54(5): 2013-2019.

LI Yujuan, ZHANG Yuanming, ZHANG Beiyu, LI Fuchang, LIU Lei. Effects of Dietary Lysine Supplementation on Hair Production Performance and Hair Follicle Development of Angora Rabbits[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(5): 2013-2019.

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