[1] |
LIN X H, LI H.Obesity:epidemiology, pathophysiology, and therapeutics[J].Front Endocrinol, 2021, 12:706978.
|
[2] |
KLEINERT M, CLEMMENSEN C, HOFMANN S M, et al.Animal models of obesity and diabetes mellitus[J].Nat Rev Endocrinol, 2018, 14(3):140-162.
|
[3] |
XU Y T, CURTASU M V, BACH KNUDSEN K E, et al.Dietary fibre and protein do not synergistically influence insulin, metabolic or inflammatory biomarkers in young obese G ttingen minipigs[J]. Br J Nutr, 2021, 125(7):828-840.
|
[4] |
CURTASU M V, SKOU HEDEMANN M, NYGAARD LÆRKE H, et al.Obesity development and signs of metabolic abnormalities in young G ttingen minipigs consuming energy dense diets varying in carbohydrate quality[J].Nutrients, 2021, 13(5):1560.
|
[5] |
ZHANG X, LERMAN L O.Investigating the metabolic syndrome:contributions of swine models[J].Toxicol Pathol, 2016, 44(3):358-366.
|
[6] |
GRAVELEY B R.Alternative splicing:increasing diversity in the proteomic world[J].Trends Genet, 2001, 17(2):100-107.
|
[7] |
疏 泽, 王立贤, 王立刚.可变剪接及其在畜禽育种中的研究与应用[J].畜牧兽医学报, 2020, 51(12):2911-2920.SHU Z, WANG L X, WANG L G.Research progress of alternative splicing and its application in livestock and poultry breeding[J].Acta Veterinaria et Zootechnica Sinica, 2020, 51(12):2911-2920.(in Chinese)
|
[8] |
BARALLE M, BARALLE F E.Alternative splicing and liver disease[J].Ann Hepatol, 2021, 26:100534.
|
[9] |
WU P, ZHANG M Y, WEBSTER N J G.Alternative RNA splicing in fatty liver disease[J].Front Endocrinol, 2021, 12:613213.
|
[10] |
DLAMINI Z, HULL R, MAKHAFOLA T J, et al.Regulation of alternative splicing in obesity-induced hypertension[J].Diabetes Metab Syndr Obes, 2019, 12:1597-1615.
|
[11] |
WONG C M, XU L, YAU M Y C.Alternative mRNA splicing in the pathogenesis of obesity[J].Int J Mol Sci, 2018, 19(2):632.
|
[12] |
LAUSTRIAT D, GIDE J, BARRAULT L, et al.In vitro and in vivo modulation of alternative splicing by the biguanide metformin[J].Mol Ther Nucleic Acids, 2015, 4(11):e262.
|
[13] |
SANTO J, LOPEZ-HERRERA C, APOLIT C, et al.Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice[J].Int J Obes, 2017, 41(3):390-401.
|
[14] |
KAMINSKA D, PIHLAJAMAKI J.Regulation of alternative splicing in obesity and weight loss[J].Adipocyte, 2013, 2(3):143-147.
|
[15] |
ZHANG K Y, TAO C, XU J P, et al.CD8+ T cells involved in metabolic inflammation in visceral adipose tissue and liver of transgenic pigs[J].Front Immunol, 2021, 12:690069.
|
[16] |
WEBSTER N J G.Alternative RNA splicing in the pathogenesis of liver disease[J].Front Endocrinol, 2017, 8:133.
|
[17] |
CARPENTER S, RICCI E P, MERCIER B C, et al.Post-transcriptional regulation of gene expression in innate immunity[J].Nat Rev Immunol, 2014, 14(6):361-376.
|
[18] |
ZHANG Y, XUE L Y, XU H, et al.Global analysis of alternative splicing difference in peripheral immune organs between tongcheng pigs and large white pigs artificially infected with PRRSV in vivo[J].Biomed Res Int, 2020, 2020:4045204.
|
[19] |
张 敏, 王 杰, 孙艳发, 等.肉鸡肌肉与脂肪组织基因组差异剪接基因分析[J].畜牧兽医学报, 2018, 49(10):2124-2132.ZHANG M, WANG J, SUN Y F, et al.Differential splicing gene analysis between muscle and fat tissues in broilers[J].Acta Veterinaria et Zootechnica Sinica, 2018, 49(10):2124-2132.(in Chinese)
|
[20] |
冉茂良, 陈 斌, 李 智, 等.基于RNA-seq测序数据鉴定和分析猪基因组可变剪接事件[J].中国科学:生命科学, 2016, 46(3):274-284.RAN M L, CHEN B, LI Z, et al.Identification and analysis of alternative splicing events in Sus scrofa using RNA-seq data[J].Scientia Sinica Vitae, 2016, 46(3):274-284.(in Chinese)
|
[21] |
CIOFFI F, SENESE R, LASALA P, et al.Fructose-rich diet affects mitochondrial DNA damage and repair in rats[J].Nutrients, 2017, 9(4):323.
|
[22] |
CAMBINDOBOTTO A E, MUÑOZ J C, GIONO L E, et al.Reciprocal regulation between alternative splicing and the DNA damage response[J].Genet Mol Biol, 2020, 43(1 suppl.1):e20190111.
|
[23] |
GARCÍA-MORENO J F, ROM ÃO L.Perspective in alternative splicing coupled to nonsense-mediated mRNA decay[J].Int J Mol Sci, 2020, 21(24):9424.
|
[24] |
CONWAY E M.Complement-coagulation connections[J].Blood Coagul Fibrinolysis, 2018, 29(3):243-251.
|
[25] |
SHEN C H, TUNG S Y, HUANG W S, et al.Exploring the effects of tert-butylhydroperoxide induced liver injury using proteomic approach[J].Toxicology, 2014, 316:61-70.
|
[26] |
DHARURI H, 'THOEN P A C, VAN KLINKEN J B, et al.Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss[J].Diabetologia, 2014, 57(11):2384-2392.
|
[27] |
GU L, ZHU Y H, LIN X, et al.Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis[J].Oncogene, 2020, 39(11):2437-2449.
|
[28] |
VLUGGENS A, ANDREOLETTI P, VISWAKARMA N, et al.Functional significance of the two ACOX1 isoforms and their crosstalks with PPARα and RXRα[J].Lab Invest, 2010, 90(5):696-708.
|
[29] |
WANG J J, ZHANG Y T, TSENG Y J, et al.miR-222 targets ACOX1, promotes triglyceride accumulation in hepatocytes[J].Hepatobiliary Pancreat Dis Int, 2019, 18(4):360-365.
|
[30] |
MOYLAN C A, PANG H, DELLINGER A, et al.Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease[J].Hepatology, 2014, 59(2):471-482.
|
[31] |
HUANG X L, LIU J G, MO X W, et al.Systematic profiling of alternative splicing events and splicing factors in left- and right-sided colon cancer[J].Aging, 2019, 11(19):8270-8293.
|
[32] |
ZHANG L, YANG H C, ZHANG W B, et al.Clk1-regulated aerobic glycolysis is involved in glioma chemoresistance[J].J Neurochem, 2017, 142(4):574-588.
|
[33] |
UZOR S, ZORZOU P, BOWLER E, et al.Autoregulation of the human splice factor kinase CLK1 through exon skipping and intron retention[J].Gene, 2018, 670:46-54.
|
[34] |
KIM M J, YU C Y, THEUSCH E, et al.SUGP1 is a novel regulator of cholesterol metabolism[J].Hum Mol Genet, 2016, 25(14):3106-3116.
|
[35] |
NOH J H, KIM K M, IDDA M L, et al.GRSF1 suppresses cell senescence[J].Aging, 2018, 10(8):1856-1866.
|
[36] |
NOH J H, KIM K M, PANDEY P R, et al.Loss of RNA-binding protein GRSF1 activates mTOR to elicit a proinflammatory transcriptional program[J].Nucleic Acids Res, 2019, 47(5):2472-2486.
|
[37] |
AZEVEDO FOINQUINOS G, AZEVEDO ACIOLI M E, SANTANA CAVALCANTI A H, et al.Influence of LGALS3 and PNPLA3 genes in non-alcoholic steatohepatitis (NASH) in patients undergone bariatric surgery[J].Obes Res Clin Pract, 2020, 14(4):326-332.
|
[38] |
AUNG L H H, YIN R X, WU D F, et al.Association of the variants in the BUD13-ZNF259 genes and the risk of hyperlipidaemia[J].J Cell Mol Med, 2014, 18(7):1417-1428.
|
[39] |
LIN E, KUO P H, LIU Y L, et al.Association and interaction of APOA5, BUD13, CETP, LIPA and health-related behavior with metabolic syndrome in a Taiwanese population[J].Sci Rep, 2016, 6:36830.
|
[40] |
ZHANG L L, YOU Y Y, WU Y H, et al.Association of BUD13 polymorphisms with metabolic syndrome in Chinese population:a case-control study[J].Lipids Health Dis, 2017, 16(1):127.
|
[41] |
BHATE A, PARKER D J, BEBEE T W, et al.ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation[J].Nat Commun, 2015, 6:8768.
|
[42] |
HYUN J, SUN Z L, AHMADI A R, et al.Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis[J].J Clin Invest, 2020, 130(4):2129-2145.
|
[43] |
KOBAYASHI M, DEGUCHI Y, NOZAKI Y, et al.Contribution of PGC-1α to obesity- and caloric restriction-related physiological changes in white adipose tissue[J].Int J Mol Sci, 2021, 22(11):6025.
|
[44] |
ZHANG R N, SHEN F, PAN Q, et al.PPARGC1A rs8192678 G>A polymorphism affects the severity of hepatic histological features and nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease[J].World J Gastroenterol, 2021, 27(25):3863-3876.
|
[45] |
WANG Q L, ZHAO B, ZHANG J, et al.Faster lipid β-oxidation rate by acetyl-CoA carboxylase 2 inhibition alleviates high-glucose-induced insulin resistance via SIRT1/PGC-1α in human podocytes[J].J Biochem Mol Toxicol, 2021, 35(7):e22797.
|
[46] |
TAUER J T, BORASCHI-DIAZ I, AL RIFAI O, et al.Male but not female mice with severe osteogenesis imperfecta are partially protected from high-fat diet-induced obesity[J].Mol Genet Metab, 2021, 133(2):211-221.
|
[47] |
ZHAO Y C, WANG F, GAO L C, et al.Ubiquitin-specific protease 4 is an endogenous negative regulator of metabolic dysfunctions in nonalcoholic fatty liver disease in mice[J].Hepatology, 2018, 68(3):897-917.
|