Acta Veterinaria et Zootechnica Sinica

   

Effects and Mechanism of Faecal Microbiota Transplantation on Intestinal Barrier Function in Piglets

  

  • Received:2020-08-25 Revised:2020-12-11 Published:2020-12-16

Abstract: Intestinal barrier is an important defense against infection. Diarrhea in piglets, mainly caused by intestinal biological imbalance and damage of barrier function, has brought extremely losses to the porcine industry. Due to the unique advantages in various intestinal diseases related to intestinal microbiota, faecal microbiota transplantation has been introduced into exploratory researches on improvement of the intestinal barrier function in piglets as a new microbiota manipulation strategy. This article reviews the structures and functions of intestinal barrier and the effects of faecal microbiota transplantation on it in piglets, then discusses the possible inner mechanisms, with the expectation to provide some references in this field.

Key words: Faecal Microbiota Transplantation, Piglet, Intestinal Barrier Function, Mechanism, Microbiota