ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2012, Vol. 43 ›› Issue (5): 816-820.doi:

• 临床兽医 • Previous Articles     Next Articles

Effect of Baihu Soup and Qinlian Liquid on the Classical Pathway of Complement Activation in Rabbit with Qifen Syndrome

ZHANG Shidong, WANG Dongsheng, WANG Xurong, LI Shihong， LI Jinyu, CHEN Jiongran, LI Hongsheng, YAN Zuoting*   

  1. Lanzhou Institute of Husbandry and Pharmaceutical Science of CAAS; Key Laboratory of Veterinary Pharmaceutics Discovery of Ministry of Agriculture; Research Center of Clinical Veterinary Medicine of CAAS; Engineering & Technology Research Center of Traditional Chinese Veterinary Medicine of Gansu Province, Lanzhou 730050, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2012-05-28 Published:2012-05-28
  • Contact: YAN Zuoting

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Abstract: The objective of this study was to compare the curative effect of Baihu Soup with Qinlian Liquid in molecular angle. The animal model of Qifen Syndrome was found through intravenous (i.v.) injection of LPS, and the model was treated with Baihu Soup and Qinlian Liquid respectively. Before and after treatment, the expression changes of serum CH50, C3 and CRP gene in liver tissue were determined by ELISA and realtime quantitative PCR respectively. The results demonstrated that complement system was activated through classical pathway. Baihu Soup can cured the animals through make genes of C3 and CRP high expression, and Qinlian Liquid plays a certain role only through upregulated the gene expression of CRP. The curative effect of Baihu Soup on animal Qifen Syndrome is superior to that of Qinlian Liquid.