Abstract: Thirty microsatellite loci were used to analyze the genetic diversity of 240 goats of Chinese six populations including Aerbasi, Erlangshan, Wuzhumuqin, Alashan, Liaoning and Shannan white goat. Based on the allele frequency, we calculated that mean heterozygosity（He）were from 0.367 to 0.467; mean polymorphism information contents（PIC）from 0.533 to 0.639 and mean effective number of alleles（Ne）from 2.571 to 4.915. Genetic variation within breed and among breeds were analyzed in the study. We clustered the NJ tree according to the Nei standard genetic distances, the result showed that six goat breeds were divided into two clusters. The study provides some clue for conservation and utilization of goat breed in the future.