ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2010, Vol. 41 ›› Issue (10): 1333-1336.doi:

• 基础兽医 • Previous Articles     Next Articles

Research on Change of Acute Phase Protein and IL-6 in Cows with Endometritis

LI De-jun1,2，Liu Yun-feng1, PEI Xiao-ying2, GUO Ding-zong2*   

  1. 1. College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China;2. College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-10-25 Published:2010-10-25

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Abstract: To observe the changes of acute phase protein and IL-6 in the serum and uterine secretions in cattle with endometritis and search their significance on diagnose. Sixty-eight cows were selected and divided into three groups: N（Normal cows）, SE（Subclinical Endometritis）and CE (Clinical endometritis). The concentration of acute phase proteins and cytokine in serum and uterine secretions of endometritis cows were detected.The results showed that the concentrations of CRP, Hp, SAA and IL-6 in the serum and uterine secretions of cows with clinical endometritis and subclinical endometritis were higher than that of control group（P＜0.01）, and group CE was significant variable than group SE, but Hp and SAA were not detected in control group. The concentration of CRP, Hp, SAA and IL-6 were increased by different degree bacterial contamination in uterine and they can be the sensitive index for diagnosis with endometritis inflammation.