不同生长时期梅花鹿鹿茸差异蛋白质组学分析

doi:10.11843/j.issn.0366-6964.2016.03.010

Abstract

Abstract:

To understand the velvet antler development mechanism in the level molecular biology，proteome differences of the sika deer velvet antlers aged 10，40，60 and 130 d were compared using 2-DE，mass spectrometry and bioinformatics.Therefore，46 proteins were altered their expressions in the sika deer velvet antlers aged 10，40，60 and 130 d，which were involved in cytoskeleton，transportation，signal transduction，apoptotic process，bone development，protein synthesis，nucleotide biosynthesis，immunity，energy metabolism，cell proliferation and antioxidant activity and protein folding.We focused on the proteins involved in bone development，antioxidant activity and apoptotic process due to the special growth process with rapidly growth and ossification.Therefore，The results showed that several proteins(P4HB，SPARC，peroxiredoxin 2，peroxiredoxin 4，galectin 1 and retinoic acid binding protein 1) might play vital role in the velvet antler growth and ossification process.Taken together，the result provided a basis for further research on the molecular mechanisms involved in the accelerated growth and ossification of deer velvet antler.

CLC Number:

S825.2

ZHANG Ran-ran，LIU Hua-miao，SHAO Yuan-chen，ZHOU Pan-yi，SU Ying，WANG Lei，XING Xiu-mei. Comparative Proteomic Analysis in Different Growth Stages of Sika Deer Velvet Antler[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2016, 47(3): 493-501.

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Comparative Proteomic Analysis in Different Growth Stages of Sika Deer Velvet Antler

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