ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2006, Vol. 37 ›› Issue (7): 646-649.doi:

• 遗传繁育 • Previous Articles     Next Articles

Study on RBP4 as a Candidate Gene for Prolificacy of Small Tailed Han Sheep

HE Yuan-qing;GUO Xiao-hong;WANG Jin-yu;CHU Ming-xing;FANG Li;YE Su-cheng; ZHOU Zhong-xiao   

  1. 1.College of Animal Science and Technology, Yangzhou University, Yangzhou 225009,China;2.College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China;3. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100094, China;4.College of Animal Science and Technology, Shanxi Agricultural University, Taigu 030801, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2006-07-25 Published:2006-07-25

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Abstract: Retinol binding protein 4（RBP4）gene was studied as a candidate gene on the prolificacy of Small Tailed Han sheep. The single nucleotide polymorphism of RBP4 gene in both high fecundity sheep breeds (Small Tailed Han sheep, Hu sheep) and low fecundity sheep breeds (Dorset sheep, Suffolk sheep) was analyzed by PCR-SSCP. There was PCR-SSCP polymorphism in four sheep breeds. BB genotype was only detected in high fecundity sheep breeds, AA genotype was only detected in Small Tailed Han sheep and Dorset sheep With decreasing fecundity in sheep, AB genotype frequency increased. The ewes with genotype BB had 0.52 (P＜0.05) and 0.67 (P＜0.05) lambs more than those with genotype AA and AB in Small Tailed Han sheep, respectively. These results showed that the studied loci of RBP4 gene had relationship with high fecundity of Small Tailed Han sheep.