Acta Veterinaria et Zootechnica Sinica ›› 2025, Vol. 56 ›› Issue (7): 3080-3087.doi: 10.11843/j.issn.0366-6964.2025.07.004

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Research Progress of Single-Cell Sequencing Technology in the Growth and Development Process of Sheep Ovaries

WEI Kangkang1(), MA Gui1, LI Wendi1, TIAN Yu1, ZHANG Lingkai1, ZHU Jihong2, HU Yamei1,*()   

  1. 1. Key Laboratory of Ruminant Molecular and Cellular Breeding of Ningxia Hui Autonomous Region, College of Animal Sciences and Technology, Ningxia University, Yinchuan 750021, China
    2. Ningxia Hui Autonomous Region Livestock Workstation, Yinchuan 750000, China
  • Received:2024-12-11 Online:2025-07-23 Published:2025-07-25
  • Contact: HU Yamei E-mail:wkk2627927534@163.com;huyamei@nxu.edu.cn

Abstract:

High-throughput single-cell sequencing technology has become an important tool for analyzing the composition information of different cells. Through this technology, the genetic characteristics of sample cells can be analyzed with high precision, revealing the gene structure and expression status of cells in complex samples, and reflecting the heterogeneity between cells. This paper summarizes the research results of single-cell sequencing technology on the development mechanism of different types of ovarian cells in the process of sheep ovarian growth and development.The use of single-cell sequencing technology can provide a more comprehensive understanding of the molecular characteristics, functional differences, and intercellular interactions of different cell types in sheep ovaries, providing new ideas and methods for in-depth research on the physiological functions of sheep ovaries and the diagnosis and treatment of related diseases.

Key words: single-cell sequencing, sheep ovaries, cellular heterogeneity

CLC Number: