家畜囊胚质量评价指标的研究进展与前沿探索

doi:10.11843/j.issn.0366-6964.2026.01.003

畜牧兽医学报 ›› 2026, Vol. 57 ›› Issue (1): 22-29.doi: 10.11843/j.issn.0366-6964.2026.01.003

家畜囊胚质量评价指标的研究进展与前沿探索

王彦博¹^,³(), 张笑梦¹, 冯肖艺¹, 宋浩然¹, 董建华¹, 潘红梅²(), 赵学明¹()

^1.中国农业科学院北京畜牧兽医研究所，北京 100193
^2.重庆市畜牧科学院，荣昌 402460
^3.山西农业大学动物科学学院，太谷 030801

收稿日期:2025-05-30 出版日期:2026-01-23 发布日期:2026-01-26
通讯作者: 潘红梅,赵学明 E-mail:wyb19834362834@163.com;panhm_2118@163.com;zhaoxueming@caas.cn
作者简介:王彦博，硕士生，主要从事动物繁殖研究，E-mail： wyb19834362834@163.com
基金资助:
重庆市人民政府与中国农业科学院战略合作资助项目（重庆地方猪胚胎冷冻保存技术研究与猪育种新材料创制,23310）;国家重点研发计划政府间重点专项(2022YFE0100200);国家自然科学基金国际合作项目(32161143032);农业农村部和财政部资助：现代农业产业技术体系资助(CARS-36-16);国家家养动物种质资源库;中国农业科学院科技创新工程(ASTIP-IAS06)

Research Progress and Frontier Exploration of Quality Evaluation Indicators for Domestic Animal Blastocysts

WANG Yanbo¹^,³(), ZHANG Xiaomeng¹, FENG Xiaoyi¹, SONG Haoran¹, DONG Jianhua¹, PAN Hongmei²(), ZHAO Xueming¹()

^1.Institute of Animal Science，Chinese Academy of Agricultural Sciences，Beijing 100193，China
^2.Chongqing Academy of Animal Science，Rongchang 402460，China
^3.College of Animal Science，Shanxi Agricultural University，Taigu 030801，China

Received:2025-05-30 Online:2026-01-23 Published:2026-01-26
Contact: PAN Hongmei, ZHAO Xueming E-mail:wyb19834362834@163.com;panhm_2118@163.com;zhaoxueming@caas.cn

摘要/Abstract

摘要：

囊胚质量评估对辅助生殖技术（assisted reproductive technology，ART）有重要意义。通过质量评估，可以筛选出具有最高着床潜力的囊胚，减少胚胎移植次数并提高临床妊娠率。然而，关于囊胚质量评估的方法有很多，但却缺乏横向和系统的比较。目前，现有的囊胚质量评估方法主要包括形态学评估、代谢组学、延时检测技术、基因筛查技术、人工智能技术等。本文通过总结目前现有的研究体系以及全面讨论各种囊胚质量评价技术的优势和局限性系统地描述和比较现阶段最有效和最广泛使用的囊胚期胚胎质量评估方法。同时，根据各种方法局限性给出了优化方案。为进一步优化囊胚期质量评价技术、提高临床妊娠率和提升胚胎选择效率提供理论依据和技术支持。

关键词: 囊胚期胚胎, 质量评价, 前沿探索, 研究进展

Abstract:

The evaluation of blastocyst quality is of great significance for assisted reproductive technology （ART）. Through quality assessment， blastocysts with the highest implantation potential can be selected， reducing the number of embryo transfers and improving the clinical pregnancy rate. However， there are many methods for blastocyst quality evaluation， but there is a lack of horizontal and systematic comparison. At present， the existing blastocyst quality evaluation methods mainly include morphological evaluation， metabolomics， time-lapse monitoring technology， genetic screening technology， artificial intelligence technology， etc. This paper systematically describes and compares the most effective and widely used methods for evaluating the quality of blastocysts at the blastocyst stage by summarizing the existing research systems and comprehensively discussing the advantages and limitations of various blastocyst quality evaluation technologies. Meanwhile， optimization schemes are proposed according to the limitations of various methods. It provides a theoretical basis and technical support for further optimizing the blastocyst quality evaluation technology， improving the clinical pregnancy rate and enhancing the efficiency of embryo selection.

Key words: blastocyst stage embryo, quality evaluation, frontier exploration, research progress

中图分类号:

S814

王彦博, 张笑梦, 冯肖艺, 宋浩然, 董建华, 潘红梅, 赵学明. 家畜囊胚质量评价指标的研究进展与前沿探索[J]. 畜牧兽医学报, 2026, 57(1): 22-29.

WANG Yanbo, ZHANG Xiaomeng, FENG Xiaoyi, SONG Haoran, DONG Jianhua, PAN Hongmei, ZHAO Xueming. Research Progress and Frontier Exploration of Quality Evaluation Indicators for Domestic Animal Blastocysts[J]. Acta Veterinaria et Zootechnica Sinica, 2026, 57(1): 22-29.

图/表 1

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家畜囊胚质量评价指标的研究进展与前沿探索

Research Progress and Frontier Exploration of Quality Evaluation Indicators for Domestic Animal Blastocysts

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