副鸡禽杆菌毒力因子研究进展

doi:10.11843/j.issn.0366-6964.2023.12.005

摘要/Abstract

摘要： 副鸡禽杆菌(Avibacterium paragallinarum, Apg) 是鸡传染性鼻炎的病原菌,可以引起鸡鼻腔分泌黏液性物质、打喷嚏、眶下窦肿胀、面部水肿和结膜炎等临床症状,导致病鸡生长不良,产蛋率急剧下降,从而危害养禽生产。Apg的致病性受多种因素影响,包括荚膜、脂多糖等细胞壁结构成分和菌体分泌的功能性蛋白(如血凝素和金属蛋白酶等)。本文从生物被膜及组分、细菌分泌物、铁离子获取和利用等方面对Apg毒力因子的研究进展进行归纳和综述,以期为鸡传染性鼻炎的科学防治提供理论参考。

关键词: 副鸡禽杆菌, 毒力因子, 鸡传染性鼻炎

Abstract: Avibacterium paragallinarum (Apg) is the pathogen of infectious coryza in chickens. It induces symptoms such as nasal cavity mucus secretion, sneezing, infraorbital sinus swelling, facial edema, and conjunctivitis. These clinical manifestations lead to stunted growth and a significant decrease in egg production, posing a threat to poultry farming. The pathogenicity of Apg is influenced by various factors, including cell wall structural components like capsule and lipopolysaccharide, as well as functional proteins secreted by the cell such as hemagglutinin and metalloproteinases. This paper provides a review of the research progress on the virulence factors of Apg, focusing on the biofilm system, secretory system, and bacterial iron capture system. The aim is to offer a theoretical reference for the scientific prevention and treatment of infectious coryza in chickens.

Key words: Avibacterium paragallinarum, virulence factor, infectious coryza

中图分类号:

S852.612

支岩, 梅晨, 刘珍邑, 乌云格日乐, 王宏俊, 胡格. 副鸡禽杆菌毒力因子研究进展[J]. 畜牧兽医学报, 2023, 54(12): 4934-4942.

ZHI Yan, MEI Chen, LIU Zhenyi, WUYUN Gerile, WANG Hongjun, HU Ge. Research Progress on the Virulence Factors of Avibacterium paragallinarum[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(12): 4934-4942.

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