Abstract: The experiment was conducted to study the effect of feed style, sex and age on the lipid metabolism of Hetian chickens. The 28dHetian chickens were raised in three kinds of feed styles. The one reared in cagedfeed for 4 pens of each 30 chickens（♀15，♂15）. The other reared indoor floor for 4 floors of each 60 chickens(♀30，♂30). The third reared outdoor access for 4 pasture of each 100 chickens（♀50，♂50）. The male and female were fed separately. The chickens were slaughtered and analyzed at 56, 84 and 112 d, respectively. The results showed that the feed style , sex and age influenced significantly the lipogenesis FAS and ME mRNA levels and enzyme activity. The hepatic FAS and ME mRNA level and enzyme activity of freeranged chickens were lower significantly than that of caged chickens(P<0.05). Then the intramuscular fat(IMF), intermuscular fat(IeMF), subcutaneous fat pad(SFP) and percent of abdominal fat(PAF) levels of freeranged chickens were lower significantly than that of caged chickens(P<0.05). The hepatic FAS and ME mRNA levels increased with the age increasing. The female hepatic FAS and ME mRNA levels were higher than the male. The correlation between enzyme activity and lipid deposition indicated that the hepatic fatty acid synthase (FAS) activity was positively related with thigh intramuscular fat (T.IMF) ,IeMF, SFP and PAF and negatively with breast intramuscular fat(B.IMF). The hepatic FAS activity was significantly correlated with SFP and PAF(P<0.05). The hepatic ME activity was significantly positively correlated with B.IMF and T.IMF(P<0.05), and negatively with SFP and PAF(P>0.05).