畜牧兽医学报 ›› 2025, Vol. 56 ›› Issue (7): 3080-3087.doi: 10.11843/j.issn.0366-6964.2025.07.004

• 综述 • 上一篇    下一篇

单细胞测序技术在绵羊卵巢生长发育过程中的研究进展

魏康康1(), 马贵1, 李文迪1, 田雨1, 张令锴1, 朱继红2, 胡亚美1,*()   

  1. 1. 宁夏大学动物科技学院,宁夏回族自治区反刍动物分子与细胞育种重点实验室,银川 750021
    2. 宁夏回族自治区畜牧工作站,银川 750000
  • 收稿日期:2024-12-11 出版日期:2025-07-23 发布日期:2025-07-25
  • 通讯作者: 胡亚美 E-mail:wkk2627927534@163.com;huyamei@nxu.edu.cn
  • 作者简介:魏康康(1997-),男,河南柘城人,硕士生,主要从事动物遗传育种与繁殖的研究,E-mail:wkk2627927534@163.com
  • 基金资助:
    宁夏大学高层次人才聚培计划(03900002418);宁夏回族自治区引才专项(2024BEH04113);宁夏回族自治区重点研发计划(2024BBF01007)

Research Progress of Single-Cell Sequencing Technology in the Growth and Development Process of Sheep Ovaries

WEI Kangkang1(), MA Gui1, LI Wendi1, TIAN Yu1, ZHANG Lingkai1, ZHU Jihong2, HU Yamei1,*()   

  1. 1. Key Laboratory of Ruminant Molecular and Cellular Breeding of Ningxia Hui Autonomous Region, College of Animal Sciences and Technology, Ningxia University, Yinchuan 750021, China
    2. Ningxia Hui Autonomous Region Livestock Workstation, Yinchuan 750000, China
  • Received:2024-12-11 Online:2025-07-23 Published:2025-07-25
  • Contact: HU Yamei E-mail:wkk2627927534@163.com;huyamei@nxu.edu.cn

摘要:

高通量单细胞测序技术已成为解析不同细胞组成信息的重要工具,能够通过该技术高精准剖析样本细胞的基因特征,揭示复杂样本中的细胞基因结构和基因表达状态,进而反映细胞间的异质性。本文总结了单细胞测序技术在羊卵巢生长发育过程中对不同类型卵巢细胞发育机制的研究结果。运用单细胞测序技术,能够更全面地理解羊卵巢中不同细胞类型的分子特征、功能差异以及细胞间的相互作用,为羊卵巢生理功能的深入研究和相关疾病的诊断治疗提供新的思路和方法。

关键词: 单细胞测序, 绵羊卵巢, 细胞异质性

Abstract:

High-throughput single-cell sequencing technology has become an important tool for analyzing the composition information of different cells. Through this technology, the genetic characteristics of sample cells can be analyzed with high precision, revealing the gene structure and expression status of cells in complex samples, and reflecting the heterogeneity between cells. This paper summarizes the research results of single-cell sequencing technology on the development mechanism of different types of ovarian cells in the process of sheep ovarian growth and development.The use of single-cell sequencing technology can provide a more comprehensive understanding of the molecular characteristics, functional differences, and intercellular interactions of different cell types in sheep ovaries, providing new ideas and methods for in-depth research on the physiological functions of sheep ovaries and the diagnosis and treatment of related diseases.

Key words: single-cell sequencing, sheep ovaries, cellular heterogeneity

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