畜牧兽医学报 ›› 2023, Vol. 54 ›› Issue (10): 4003-4015.doi: 10.11843/j.issn.0366-6964.2023.10.001
罗睿杰, 曹素英*
收稿日期:
2023-05-22
出版日期:
2023-10-23
发布日期:
2023-10-26
通讯作者:
曹素英,主要从事动物繁殖学研究,E-mail:20137602@bua.edu.cn
作者简介:
罗睿杰(1999-),男,北京人,硕士生,主要从事动物繁殖学研究,E-mail:2587714111@qq.com
基金资助:
LUO Ruijie, CAO Suying*
Received:
2023-05-22
Online:
2023-10-23
Published:
2023-10-26
摘要: 多能干细胞具有无限增殖能力,可以分化产生三胚层各种组织细胞,在生物医药、动物育种等领域有广泛应用前景。大家畜干细胞可以加速育种进程,代替小鼠作为医学研究模型,生产细胞培养肉等。然而,由于家畜与人、小鼠等之间存在较大的种间差异,大家畜多能干细胞建系进程相对滞后。目前稳定的猪多能干细胞已经成功建系,而牛、羊、马等其他家畜的多能干细胞系仍存在不足。本文综述了大家畜胚胎干细胞和诱导多能干细胞建系的研究进展,并对大家畜多能干细胞在干细胞基础研究、家畜繁殖、生物医学、食品生产等领域的应用前景进行了展望。
中图分类号:
罗睿杰, 曹素英. 大家畜多能干细胞的研究进展与应用前景[J]. 畜牧兽医学报, 2023, 54(10): 4003-4015.
LUO Ruijie, CAO Suying. Research Progress and Application Prospect of Livestock Pluripotent Stem Cells[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(10): 4003-4015.
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