ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2012, Vol. 43 ›› Issue (5): 832-837.doi:

• 研究简报 • Previous Articles     Next Articles

Tissue Expression Differentiation of SLADQA Gene in Yorkshire, Sutai and Meishan

ZI Chen1, WU Zhengchang1, LIU Lu1, DU Zidong2, HUANG Xiaoguo3, 4,
YANG Jiansheng4, ZHU Guoqiang2, 3, 4, WU Shenglong1, 3, 4*, BAO Wenbin1, 3, 4*   

  1. 1. Key Laboratory for Animal Genetics, Breeding, Reproduction and Molecular Design of Jiangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China; 2. College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China; 3. Jiangsu Engineering Research Centre for Molecular Breeding of Breeder Pig, Changzhou 213149, China; 4. Jiangsu (Yangzhou) Public Technical Service Centre for Efficient and Healthy Culture Technology in Largescale Swine Farms, Yangzhou 225009, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2012-05-28 Published:2012-05-28

PDF (PC)

498

Abstract: The aim of this study was to analyse SLADQA gene expression in postweaning piglets of Yorkshire, Meishan and E. coli F18resistant resource population of Sutai by realtime PCR and to investigate the potential relationship between SLADQA gene and the different immune capacity of Chinese and exotic pig breeds, as well as the resistance to E. coli F18. SLADQA gene expression was detected in 11 tissues and the expression pattern was consitent in the three pig breeds，the expression level was the higher in lung, spleen and lymph node, the moderate in stomach, duodenum and jejunum. Meanwhile, the expression level of SLADQA gene was the highest in all tissues detected in Sutai piglets, followed by Yorkshire and Meishan. The expression level in lung, lymph node and thymus in Sutai was significantly higher than that in Meishan. In addition, there was significant difference in SLADQA gene’s expression between Sutai and Meishan pigs. From above analysis, it was concluded that SLADQA gene has important function of stimulating immune and antigen presentation in piglets’ response and physiological changes to the infection of E. coli F18.