ACTA VETERINARIA ET ZOOTECHNICA SINICA

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The Advances and Applications of Viral Metagenomics

HE Biao, TU Chang-chun*   

  1. (The Key Laboratory of Jilin Province for Zoonoses Control and Prevention, Military Veterinary Research Institute, Academy of Military Medical Sciences, Changchun 130122, China)
  • Received:2012-06-29 Online:2012-12-26 Published:2012-12-26

Abstract:

Metagenomics, an emerging microorganism-researching technology in recent years, directly focuses on the whole genetic materials of microorganism in all kinds of environment and breakthroughs limitations of traditional research methods, such as isolating culture, serologic reaction and PCR. Viral metagenomics has been used to discover many novel viruses in fields of human guts, animal tissues, blood, and sewer and so on, and help people to understand the virome constitutions in these environments as well as the enlargement of host ranges of many viruses, embodying the pragmatic significance of novel virus discovery, pathogen tracing and bioEW. This review briefly introduced the history of viral metagenomics and its definition and summarized some major applications of this technique and suggested that the analogous research should be carried out more in China.

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