ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2011, Vol. 42 ›› Issue (4): 489-494.doi:

• 遗传繁育 • Previous Articles     Next Articles

The Tissues Profile of MC3R and MC4R and the Association of Their Expressionin the Adipose with Backfat Thickness in Chinese Simmental Cattle

HUANG Meng1,2, XU Shang-zhong1,2*, LI Jun-ya2, GAO Xue2, CHEN Jin-bao2   

  1. 1. College of Animal Science and Technology, Northwest A &F University,Yangling 712100, China; 2. Institute of Animal Science, Chinese Academy ofAgricultural Sciences, Beijing 100193, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2011-04-20 Published:2011-04-20

PDF (PC)

334

Abstract: In order to explore the expression rule of key gene and screen the candidate gene affecting fat deposition, 30 samples from 137 slaughtered 18 month Chinese simmental beef cattle were divided into thick (H) and thin (L) backfat groups, and the expression of MC3R and MC4R were analyzed in the adipose of different samples and other tissues. The result indicated that both the MC3R and MC4R expressed in the heart, liver, spleen, lung, kidney, muscle, adipose, thymus, small intestine, lymph and testis. The abundances of both the MC3R and MC4R mRNA in adipose were higher in L group than those in H group (P<0.05), and correlated with backfat thickness (r=0.784, P<0.05; r=0.836, P<0.05; respectively). The results indicate that MC3R and MC4R had significant relationship with backfat thickness and might be a candidate gene for fattening in beef cattle.