Abstract: The distribution of somatostatin (SS) immunoreactive(IR) cells in Laiwu Black goat digestive system were researched by immunohistochemical SABC method. The shape of SS-IR cells were mainly ellipse and cone . SS-IR cells showed peak density in the pylorus, but not detected in the cardia, colon, cecum and rectum. In pancreatic islets ,SS-IR cells were discerned predominately in the mantle regions,meanwhile SS-IR cells were also found in the exocrine portions and the central regions. In conclusion，SS-IR cells were showed up in the pylorus and the mantle regions of the pancreatic islets mostly.