关键词: 哺乳仔猪, N-氨甲酰谷氨酸, 生长性能, 内源精氨酸合成代谢

Abstract:

This study was conducted to investigate the effects of oral administration of N-carbamoylglutamate on growth performance and the endogenous anabolism of arginine of suckling piglets from 7 to 21 days of age. The "Duroc × (Landrace × Yorkshire)" crossbred suckling piglets (n=30, 4-day-old) from 6 litters(same parity, 5 suckling piglets per litter) with similar weight((2.036±0.181) kg) were randomly allocated to five treatments (six replicates each), which were orally administrated at the dose of 0,100,150,200 and 250 mg·kg^-1BW·d^-1 NCG, respectivly. Result: ①Oral administration of 100 and 150 mg·kg^-1 BW NCG significantly increased the average daily gain of suckling piglets compared with the control piglets (P<0.05).②Oral administration of 150 mg·kg^-1BW NCG significantly increased the plasma citrulline content of suckling piglets compared with the other suckling piglets (P<0.05). ③Oral administration of 100,150 and 200 mg·kg^-1 BW NCG significantly increased the activity of carbamoyl phosphate synthase-I in duodenal of suckling piglets (P<0.05). ④Oral administration of 150 mg·kg^-1 BW NCG significantly increased the gene expression of carbamoyl phosphate synthase-I in duodenal (P<0.05); 100 and 150 mg·kg^-1 BW NCG significantly improved the gene expression of carbamoyl phosphate synthase-I(P<0.05) in jejunum and ileum. These results indicated that N-carbamoylglutamate could improve the growth performance and the endogenous anabolism of arginine of suckling piglets.

Key words: suckling piglet, N-carbamoylglutamate, growth performance, endogenous anabolism of arginine