长链非编码RNA在畜禽经济性状中的研究进展

doi:10.11843/j.issn.0366-6964.2018.10.001

摘要/Abstract

摘要：

长链非编码RNAs（long noncoding RNA，lncRNAs）是一类转录本长度>200 nt的非编码RNA（non-coding RNA，ncRNA），且广泛存在于动物、植物及微生物的细胞质和细胞核中。研究表明，LncRNA能够在染色质、转录和转录后水平调控基因表达，参与动物几乎所有的生命过程，例如繁殖、肌肉生长、脂肪沉积、毛囊生长、乳腺发育和泌乳等。本文就lncRNA的作用机制及其在畜禽经济性状研究中的现状进行了综述，旨在为lncRNA在畜牧业中的研究和应用提供理论依据。

Abstract:

Long noncoding RNAs(lncRNAs), a kind of noncoding RNA transcripts with the length more than 200 nucleotides, widely exists in cytoplasm and nuclei of animals, plants and microbes. Studies have shown that lncRNAs can regulate gene expression at chromosomal, transcriptional and post-transcriptional levels. lncRNA plays a vital role in most life processes in animals, such as reproduction, muscle growth, fat deposition, hair follicle development, mammary gland development and lactation. This paper reviews the regulation mechanism and current research status of lncRNAs in livestock economic traits, which would provide theoretical basis and practical reference for the research and application of lncRNAs in animal husbandry.

中图分类号:

S813.1

杨兵, 李晓凤, 王昕. 长链非编码RNA在畜禽经济性状中的研究进展[J]. 畜牧兽医学报, 2018, 49(10): 2063-2069.

YANG Bing, LI Xiao-feng, WANG Xin. Research Progress of Long Noncoding RNA in Economic Traits of Livestock[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2018, 49(10): 2063-2069.

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