山羊产羔数全基因组关联分析

doi:10.11843/j.issn.0366-6964.2015.04.006

Abstract

Abstract:

The aim of this study was to find and map novel genes related to lambing number in goat by genome-wide association study(GWAS).A total of 302 Yunnan Black goats from 6 families were genotyped by Illumina Goat60K iSelect array.The GWAS on goat lambing number was performed.The Results showed that 2 SNPs located at the downstream of SLC4A10 and upstream of TBR1 on chromosome 2 were significantly associated with lambing number (P<1.48E-6) at 5% genome-wide level.Five SNPs were suggestive associated with lambing number (P<2.97E-5).These 5 SNPs were located on chromosome 1，21，28，respectively，including SENP7，Hypothetical Protein，WDFY4，TMEM26 and BICC1 genes.These genes and SNPs offer essential information for understanding the molecular mechanisms of lambing number and provide foundation for the application of marker-assisted selection in breeding program of goat.

CLC Number:

S827
S813.3

LAN Rong，ZHU Lan，YAO Xin-rong，WANG Peng，SHAO Qing-yong，HONG Qiong-hua. Genome-wide Association Study of Lambing Number in Goat[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2015, 46(4): 549-554.

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Genome-wide Association Study of Lambing Number in Goat

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