ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2012, Vol. 43 ›› Issue (5): 708-716.doi:

• 遗传繁育 • Previous Articles     Next Articles

Associations of UCP2 Gene Polymorphisms with Growth Traits in Simmental

CHEN Cui, ZHANG Limin, CHEN Xiaojie, LIU Xidong, ZHANG Meng, LI Jiao, YUAN Zhengrong, ZHANG Lupei, GAO Xue,GAO Huijiang, LI Junya, XU Shangzhong*   

  1. Key Laboratory of Farm Animal Genetic Resources and Utilization of Ministry of Agriculture, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2012-05-28 Published:2012-05-28
  • Contact: XU Shangzhong*

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Abstract: The aim of this study was to analyze the association of UCP2 gene polymorphisms and haplotypes with feed conversion ratio(FCR) and growth traits in beef cattle. In this study, 118 Simmental were used, four SNPs of UCP2 gene (G118A，C161T，C215G，C305T) were genetyped by PCRRFLP in Simmental to investigate the associations of SNPs and haplotypes with FCR and growth traits. The results showed that G118A, C161T and C305T were significantly associated with FCR (P<0.05).Compared with the individuals with homozygote, the values of FCR of individuals with the heterozygote were significantly higher. However, the difference between the individuals with homozygotes were not significant. The locus C161T and C305T had an major affect on heart girth and circumference of abdomen. Among the phenotypes which were significantly different, individuals with TT genotype had a significantly higher average value than that of individuals with AA genotype. Association analysis of haplotypes indicated similar results with that of SNPs. Considered the FCR,ADG and body size traits, it was suggested that the TT genotype at locus C161T and C305T of UCP2 gene were important candidate molecular markers for improving growth traits.