ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2012, Vol. 43 ›› Issue (3): 336-342.doi:

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The Relationship between Oncogene and Oncogenesis Mechanism of Avian Leukosis/Sarcoma Viruses

CHEN Hao， WANG Yixin， ZHAO Peng， LI Jianliang， LI Deqing， CUI Zhizhong*   

  1. College of Veterinary Medicine， Shandong Agricultural University/Shandong Engineering Research Center for Animal Disease Control and Prevention， Tai’an 271018， China
  • Received:1900-01-01 Revised:1900-01-01 Online:2012-03-28 Published:2012-03-28
  • Contact: CUI Zhizhong*

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Abstract: Avian leukosis/sarcoma viruses were divided into two categories according to the difference of the activated oncogenes. Nonacute transforming virus can cause tumors by insertional activation of cellular protooncogene with a long latency, while acute transforming virus can induce a fast tumorigenesis through direct transcription of viral oncogene. This paper will review the relationship between the oncogenesis mechanism and oncogenes.