ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2012, Vol. 43 ›› Issue (8): 1186-1191.doi:

• 遗传繁育 • Previous Articles     Next Articles

Distribution Patterns of GnRH and GnRHR Positive Cells in Hypothalamus at Different Postnatal Stages in Jining Gray Goats

LIU Xiao 1,2, WANG Shuying 1,2*, YIN Yutao 1,2, ZHANG Demin 1,2,

HUANG Libo 1,2, HOU Yanmeng 1,2

  

  1. 1. College of Veterinary Medicine, Shandong Agricultural University, Tai’an 271000, China; 2. Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Technology, Shandong Agricultural University, Tai’an 271000, China
  • Received:2011-12-11 Revised:1900-01-01 Online:2012-08-24 Published:2012-08-24
  • Contact: WANG Shuying

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Abstract: In order to detect the morphological changes and distribution patterns of GnRH and GnRHR in hypothalamus at different postnatal stages in Jining Gray goats, immunohistochemical Strept Avidin BiotinPeroxidase Complex (SABC) threestep method was used to study the distribution of GnRH and GnRHR in hypothalamus in goats at 0, 2, 4 and 6 months old. The results showed that GnRH and GnRHR positive cells were widely scattered in hypothalamus. Most of the positive cells were distributed in medial preoptic area (MPA), mamillary nucleus (MB), supraoptic nucleus (SON) and suprachiasmatic nucleus (SCN). The size and number of positive cells were increased with the increase of month old. The numbers of positive GnRH and GnRHR cells were significantly higher at 2 month old (puberty) than that at birth. The results suggest that GnRH and GnRHR secreted by hypothalamus might play a pivotal role in the onset of puberty and the maintenance of maturation in Jining Gray goat at the postnatal developing stage.