ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2006, Vol. 37 ›› Issue (8): 745-748.doi:

• 遗传繁育 • Previous Articles     Next Articles

Relationship between Polymorphism of Goat MSTN Gene Intron 2 and Body Weight

LIU Zheng-zhu;LI Xiang-long;GONG Yuan-fang;JIN Xiao-min;FENG Min-shan

  

  1. 1.Department of Animal Science, Hebei Normal University of Science & Technology, Changli 066600,China；2. College of Animal Science and Technology, Hebei Agricultural University,Baoding 071001,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2006-08-25 Published:2006-08-25

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Abstract: One pair of primer for goat MSTN gene intron 2 was designed according to goat MSTN gene sequence (Accession No. DQ167575) and PCR-RFLP was carried out in a total number of 102 individuals including Boer goat and its backcrossed offspring to Tangshan dairy goat. The result of sequencing showed that there were two substitution mutations in the fragments. Statistical analysis indicated that AA genotype had significant higher weaning weight than BB and AB genotype (P<0.05).CC genotype had significant higher birth weight than CD genotype (P<0.05). It could be inferred that the MSTN gene maybe a major gene or linked to the major gene affecting the body weight. The polymorphic site could be used to marker assisted selection program for body weight.