Abstract: Ten polymorphic microsatellite loci among 4 local goat breeds (Laoshan dairy goat, Jining grey goat, Lubei white goat and Laiwu black goat) in China were used to analyse the relating effect between their alleles and growth traits, by using general linear model (GLM) and microsatellite analysis technique. The results showed that, compared with the breed, sex and age factors, microsatellite marker factor had less effect on body weight and body size traits, however, BM6404, BM1818, BM812 and BM6444 affected body weight significantly （P<0.05 or P<0.01）, and BM6404,BM1818,BMS12484,MAF70 had significant effect on main body size traits（P<0.05 or P<0.01）. We also found that，allele 130 of BM6404 had positive effect on heart girth, height at withers and thurl width, allele 120 had negative effect on heart girth, and positive effect on height at withers and rump length; allele 168 had negative effect on rump length and thurl width. For MAF70, allele 142 had positive effect and allele 178 had negative effect on body length respectively. For BMS1248, allele 128 had positive effect on circumference of cannon bone.