ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2006, Vol. 37 ›› Issue (3): 309-312.doi:

• 研究简报 • Previous Articles    

Mapping CACNA1S Gene in Porcine by Radiation Hybrid Panel

FANG Xiao-min;ZHAO Xiao-feng;GUO Xiao-ling; XU Ning-ying   

  1. College of Animal Science, Zhejiang University, Hangzhou 310029, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2006-03-25 Published:2006-03-25

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Abstract: CACNA1S gene encodes the α1 subunit of Calcium channel. The mutation of CACNA1S gene can lead to hypokalemic periodic paralysis in human and Malignant hyperthermia in porcine. Primers were designed according to the published human CACNA1S sequences for amplification of porcine CACNA1S gene. PCR products were sequenced and compared with that of human. CACNA1S gene was located at 10p11-12 in porcine by IMpRH panel (INRA-University of Minnesota porcine Radiation Hybrid panel).