ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2007, Vol. 38 ›› Issue (8): 765-768.doi:

• 遗传繁育 • Previous Articles     Next Articles

Polymorphism of FcRn Gene and Its Effects on the Sow Colostrum IgG Concentration

WANG Bing-yan;WANG Li-xian;WANG Ting;ZHAI Li-wei;WANG Chu-duan;LI Zhen-kuan;ZHOU Wei-liang   

  1. 1 Key Laboratory of Animal Genetics and Breeding, Ministry of Agriculture, Beijing 100094，China;2College of Animal Science and Technology, China Agricultural University, Beijing 100094,China; 3Institute of Animal Science, Chinese Academy of Agricultural Sciences,Beijing 100094，China;4Tianjin Ninghe Pig Breeding Farm, Tianjin 301504,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-08-25 Published:2007-08-25

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Abstract: The polymorphism of the FcRn gene was analyzed, and two SNPs were found by the technique of single strand conformation polymorphism (SSCP) and finally confirmed by sequencing. The frequencies of different genotypes in 207 sows of the three breeds were calculated and the relationship between three genotypes and IgG Concentration in Colostrum of the Sow were analyzed based on liner model. The results showed that the mutation in the Site1 did not have effect on IgG concentration in colostrum of the sows( P>0.05) , the mutation in the Site6 had effect on IgG concentration in colostrum of the sows ( P<0.05); Multiple t comparisons in site6 indicated that IgG concentration in colostrum of the sows between CC,CD and DD genotype were significant(P<0.05)：IgG concentration in colostrum of the sows of CC is the highest, while that of the sows of DD is the lowest. The result indicated FcRn gene could be a candidate gene of IgG concentration in colostrum of the sows.