ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2005, Vol. 36 ›› Issue (7): 690-694.doi:

• 兽医 • Previous Articles     Next Articles

Expression of Estrogen Receptor and Low-density Lipoprotein Receptor in Tissues of Atherosclerotic Rabbit

CUI Ya-li;ZHAO De-ming;LIANG Wan-ning;NING Zhang-yong;YANG Jian-min;SUN Yan-ming   

  1. 1. College of Veterinary Medicine, China Agricultural University, Beijing 100094，China;2. College of Animal Science and Technology, Agricultural University of Hebei,Baoding 071001,China； 3. The 466th Hospital of PLA, Beijing 100081,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2005-07-25 Published:2005-07-25

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Abstract: In present study, atherosclerotic animal model were replicated with high cholesterol feedstuff , and the expressions of estrogen receptor α and low-density lipoprotein receptor mRNA in heart and liver were studied by half quantitive RT-PCR, the rabbits oophorectomized and fed with normal feedstuff were used as control．The results showed：the two sorts of receptors expressed in heart and liver；in control group, the relative expression of ERα mRNA in the heart and liver were 0.43±0.12, 0.39±0.20，the relative expression of low-density lipoprotein receptor mRNA in the heart and liver were 0.27±0.05, 0.86±0.12； The relative expression of estrogen receptor and low-density lipoprotein receptor mRNA in the heart and liver of model rabbits were 0.29±0.03, 0.27±0.06 and 0.04±0.01, 0.17±0.02 respectively．