ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2009, Vol. 40 ›› Issue (7): 1101-1105.doi:

• 研究简报 • Previous Articles     Next Articles

Quantitative Expression of Vascular Endothelial Growth Factor Gene and Hypoxic Adaptation in Tibetan Chicken

CHAMBA Yangzom 1, XIE Zhuang 2, SHANG Peng 1 , LI Qifa 2, ZHAI Mingxia 2, ZHANG Hao 3*
  

  1. 1. College of Agriculture and Animal Husbandry, Tibet University, Linzhi 860000, China; 2. College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China; 3. College of Animal Science and Technology, China Agricultural University, Bejing 100193，China
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-07-24 Published:2009-07-24
  • Contact: ZHANG Hao

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Abstract: In this study, the expression of VEGF gene was measured in chorioallantoic membrane (CAM) tissue of Tibetan chickens and Dwarf Recessive White chickens which were incubated at normoxia (O2，21%) and hypoxia (O2，13%), respectively. The results showed that hypoxiainduced VEGF upregulation occurred in CAM tissue for both breeds. However, the extent of upregulation was significantly higher in Dwarf Recessive White chickens than that in Tibetan chickens. It concluded that hypoxia induced VEGF mRNA expression to a certain degree in Tibetan, which made for angiogenesis and adaptation to hypoxic environment for Tibetan chickens. However, the VEGF expression was excess in CAM tissue in Dwarf Recessive White chickens at hypoxic condition, which made the embryo of Dwarf Recessive White chickens against to development and survival.