Abstract: By use of PCR-SSCP approach, the present study analyzed the single nucleotide polymorphism (SNP) at G3072A site of IGF2 intron 3 in Yorkshire, Landrace and Duroc pigs. The association of the polymorphism with birth weight and early growth traits were as well analyzed in Yorkshire pigs. The results indicated that the genotypes AA,AB and BB were found in Yorkshire, Landrace and Duroc pig populations, and the populations of both Yorkshire and Landrace pigs were in a state of Hardy-Weinberg equilibrium(P＜0.01),whereas the Duroc pig population was not(P＞0.05). Sequencing demonstrated that A and B alleles correspond to nucleotide A and G, respectively. In addition, for A allele, a (AG) dinucleotide was inserted at the 10-11^th position downstream the mutation site. Association analysis indicated that the least square means of birth weight of AA, AB and BB pigs differ significantly (P＜0.05), whereas body weight at 21, 28 and 70 days and average daily gain of body weight from birth to 21 days,from 21 days to 28 days and from 28 to 70 days of AA and AB individuals were not significantly different in Yorkshire pigs（P>0.1）.