ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2005, Vol. 36 ›› Issue (9): 974-976.doi:

• 研究简报 • Previous Articles     Next Articles

Effects of Lipopolysaccharide on the Production of Nitric Oxide in Intestinal Mucosa Microvascular Endothelial Cells in vitro

DUAN Hui-qin;QIAO Jian;ZHANG Yong-dong;SUO Zhan-wei;MU Xiang;XU Jian-qin   

  1. 1. College of Veterinary Medicine, China Agricultural University, Beijing 100094, China;2.Faculty of Animal Science and Technology, Beijing Agricultural College, Beijing 102206, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2005-09-25 Published:2005-09-25

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Abstract: The effect of lipopolysaccharide（LPS）on the production of NO in primary cultures of rat intestinal mucosa microvascular endothelial cells(RIMEC)was investigated . RIMEC weve in culture exposed to the inflammatory cytokine LPS. Stable NO production, which accumulated in the culture medium without LPS in a linear way for 24 h . LPS induced NO production in RIMEC in a time-dependent manner. These data indicate that LPS triggered endothelial cells activation, the production of NO was enhanced.