猪脂肪发育相关miRNAs的功能研究进展

doi:10.11843/j.issn.0366-6964.2015.12.001

Abstract

Abstract:

Adipose tissue，an important factor that affects the porcine carcass quality，is closely related with the pork quality.Understanding the regulation mechanisms of adipose tissue development and fat metabolism are important to the animal husbandry production and disease treatment.miRNAs(microRNAs) are a class of endogenous，non-coding，small RNA molecules，which are typically 18-24 nucleotides(nt) in length.miRNAs play an important role in the regulation of gene expression at the post-transcriptional level.A large number of evidences demonstrated that miRNAs have influence on diverse biological processes，such as preadipocyte differentiation，adipogenesis，fatty acid metabolism and cholesterol biosynthesis.However，only 326 porcine miRNAs has been currently reported and rare studies could be read about the porcine miRNAs that regulate the fat development.Herein，it is reviewed that the studies on the discovery and identification of fat-associated miRNAs in pigs in this paper，and the progress on the research of porcine miRNAs that regulate fat development are also summarized.

CLC Number:

S828
S813.3

CHEN Chen，HU Xiong-gui，ZHU Ji，REN Hui-bo，DENG Yuan，PENG Ying-lin. Progress on the Research of miRNAs Associated with Fat Development in Pigs[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2015, 46(12): 2117-2126.

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Progress on the Research of miRNAs Associated with Fat Development in Pigs

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