山羊支原体肺炎的CT影像分析

doi:10.11843/j.issn.0366-6964.2021.05.027

畜牧兽医学报 ›› 2021, Vol. 52 ›› Issue (5): 1414-1423.doi: 10.11843/j.issn.0366-6964.2021.05.027

山羊支原体肺炎的CT影像分析

姜敏¹, 姚大伟¹, 田睿², 毛立², 史超颖³, 李文良², 张纹纹², 李基棕², 杨蕾蕾², 孙敏², 杨德吉¹, 刘茂军^2*

1. 南京农业大学动物医学院, 南京 210095;
2. 江苏省农业科学院兽医研究所/农业部兽用生物制品工程技术重点实验室, 南京 210019;
3. 南京艾贝尔动物医学中心, 南京 210046

收稿日期:2020-09-24 出版日期:2021-05-23 发布日期:2021-05-22
通讯作者: 杨德吉,主要从事兽医影像诊断学研究,E-mail:djyang@njau.edu.cn;刘茂军,主要从事动物传染病学研究,E-mail:maojunliu@163.com
作者简介:姜敏(1994-),女,湖南益阳人,硕士生,主要从事动物MRI、CT影像诊断技术研究,E-mail:jiangmin82@vip.qq.com;姚大伟(1979-),男,山东枣庄人,副教授,主要从事兽医影像学研究,E-mial:yaodawei@njau.edu.cn。
基金资助:
国家重点研发计划项目（2017YFD0502200）；中央高校基本科研业务费专项（KYYJ201809）；江苏省第五期“333高层次人才培养工程”科研项目（BRA2019092）

Computer Tomography Images Analyses of Mycoplasma Pneumonia of Goats

JIANG Min¹, YAO Dawei¹, TIAN Rui², MAO Li², SHI Chaoying³, LI Wenliang², ZHANG Wenwen², LI Jizong², YANG Leilei², SUN Min², YANG Deji¹, LIU Maojun^2*

1. College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China;
2. Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Nanjing 210019, China;
3. Nanjing Ai-bi Pet Medical Center, Nanjing 210046, China

Received:2020-09-24 Online:2021-05-23 Published:2021-05-22

摘要/Abstract

摘要： 旨在研究羊感染肺炎支原体后胸部CT影像学特征。将20只山羊分为2组，对照组5只、试验组15只，试验组通过气管注射感染5 mL绵羊肺炎支原体（1×10⁷ CCU·mL^-1）人工诱发山羊支原体肺炎，对照组注射等体积生理盐水。感染后观察两组羊的临床症状，在感染后第0、7、14、21、28天对两组羊胸部进行CT扫查，分析支原体肺炎的CT影像学特征。感染后第29天剖杀羊，观察肺部病理解剖变化。取病变组织制备石蜡切片，观察组织病理学变化。结果显示：试验组山羊感染肺炎支原体后表现出呼吸道感染症状，体温升高，咳嗽，流浆液性或脓性鼻液。胸部CT影像主要表现为片状磨玻璃密度影，网格状阴影，多见双侧肺叶病变，好发于右前叶，以间质性肺炎伴发支气管肺炎为主，其中，重症羊多见空气支气管征，个别羊见胸膜增厚影。对照组临床症状和胸部CT影像在感染前后未见明显差异和异常。综上表明，CT影像诊断技术有利于羊支原体肺炎的早期诊断，并有助于疾病转归的判断。

关键词: 羊, 支原体, 肺炎, 计算机断层扫描

Abstract: The aim of this study was to investigate the characteristics of computer tomography images after Mycoplasma ovipneumoniae infection in goats. Twenty 1-year-old goats were randomly divided into the control group (n=5) and the experimental group (n=15). In the experimental group, mycoplasma pneumonia was artificially induced by intratracheal injection with 5 mL Mycoplasma ovipneumoniae standard strain IK3-3 (1×10⁷ CFU·mL^-1), the control group was injected with equal volume physiological saline. After inoculation, the clinical symptoms of the two groups were observed. At the same time, CT scan was performed on the chest at day 0, 7, 14, 21 and 28 after infection to analyze the characteristics of images. The goats were killed at day 29 after infection to observe the pathological and histopathological changes between the two groups. As a result, after successful infection, the experimental goats expressed obvious clinical symptoms of respiratory diseases, such as high temperatures, cough, serous and purculent nasal discharge. In the experimental group, CT images were mainly characterized by ground glass density shadow and mesh shadow, mostly in bilateral lobar lesions, preferably in the right anterior lobe. Interstitial pneumonia with bronchopneumonia was the main characteristic. In addition, air bronchogram was observed in severe group’s cases and thickened pleural was found in some cases. There was no significant difference before and after infection in normal group goats. It was suggested that CT technology was conducive for the early diagnosis of mycoplasma pneumoniae in goats and helpful to judge the outcomes.

Key words: goat, Mycoplasma ovipneumonia, pneumonia, computed tomography

中图分类号:

S854.7

姜敏, 姚大伟, 田睿, 毛立, 史超颖, 李文良, 张纹纹, 李基棕, 杨蕾蕾, 孙敏, 杨德吉, 刘茂军. 山羊支原体肺炎的CT影像分析[J]. 畜牧兽医学报, 2021, 52(5): 1414-1423.

JIANG Min, YAO Dawei, TIAN Rui, MAO Li, SHI Chaoying, LI Wenliang, ZHANG Wenwen, LI Jizong, YANG Leilei, SUN Min, YANG Deji, LIU Maojun. Computer Tomography Images Analyses of Mycoplasma Pneumonia of Goats[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(5): 1414-1423.

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山羊支原体肺炎的CT影像分析

Computer Tomography Images Analyses of Mycoplasma Pneumonia of Goats

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